GuidelineGastroenterology2021
AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review.
Guideline in Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07625267 (Non-antibiotic Management in Acute Uncomplicated Diverticulitis), which is not on this map. Cited by 91 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-antibiotic Management in Acute Uncomplicated Diverticulitis: Randomized Open Label-controlled Trial
Who cites it
91 citing papers in PubMed, 5 syntheses or guidelines pooled it, 167 citations in OpenAlex.
- Systematic review and meta-analysis on key controversies in the management of diverticular disease: a multi-society collaboration.Surgical endoscopy · 2026Pooled it
- Are Nuts Safe in Diverticulosis? A Mixed-Methods Systematic Review of Available Evidence.Nutrients · 2025Pooled it
- SAGES white paper on antibiotic omission in the management of acute uncomplicated diverticulitis: why, when, who, and most importantly, how.Surgical endoscopy · 2025Guideline
- Genetic, epigenetic and environmental factors in diverticular disease: systematic review.BJS open · 2024Pooled it
- Preventing acute diverticulitis. any roles for non-absorbable antibiotics? in search of evidence: a systematic review, meta-analysis, and trial sequential analysis.Frontiers in gastroenterology (Lausanne, Switzerland) · 2023Pooled it
- A prospective, randomized, double-blind, placebo-controlled trial of the Kampo formula daiobotanpito combined with antibiotic therapy for acute diverticulitis.Scientific reports · 2025Trial
- Patient-centered online health information on diverticulitis: Assessing the readability, content, and overall quality.American journal of surgery · 2026Article
- EAES-SAGES clinical practice guideline update: multi-society recommendations on key controversies in the management of diverticular disease.Surgical endoscopy · 2026Article
- Natural Language Processing Algorithm Accurately Classifies Diverticulitis-Related Complications and Predicts Long-Term Outcomes.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Article
- Early Computed Tomography Imaging and Clinical Outcomes in Hospitalized Patients with Acute Diverticulitis: A Propensity-Matched Multicenter Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Routine colonoscopy after acute diverticulitis.Proceedings (Baylor University. Medical Center) · 2026Article
- Reevaluating the role of routine colonoscopy after acute diverticulitis: impact on colon cancer and advanced adenoma detection across age groups.Proceedings (Baylor University. Medical Center) · 2026Article
- Evidence-based clinical practice guidelines for diagnosis and medical management of acute colonic diverticulitis developed by the Korean Association for the Study of Intestinal Diseases (KASID).Intestinal research · 2026Review
- Early risk stratification of acute diverticulitis using procalcitonin, CRP, and CT imaging: A retrospective analysis.Turkish journal of surgery · 2026Article
- Association between diabetes mellitus and diverticulosis: a cross-sectional analysis.Wiener klinische Wochenschrift · 2026Article
- Utility of Colonoscopy After Acute Colonic Diverticulitis.Diagnostics (Basel, Switzerland) · 2026Review
- Colonoscopy After Acute Diverticulitis: Low Yield in Uncomplicated Disease, Higher Risk in Complicated Cases.Cureus · 2026Article
- Genetic Risk, Healthy Lifestyle, and Risk Stratification for Diverticulitis.Journal of the American College of Surgeons · 2026Article
- COVID-19 Infection in a Patient With Sigmoid Diverticulitis: Viral Diverticulitis or Incidental Association?Cureus · 2026Article
- Is common variable immunodeficiency associated with diverticulitis? A matched cohort study.Annals of gastroenterology · 2026Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for patients with this disease. The purpose of this Clinical Practice Update is to provide practical and evidence-based advice for management of diverticulitis. We reviewed systematic reviews, meta-analyses, randomized controlled trials, and observational studies to develop 14 best practices. In brief, computed tomography is often necessary to make a diagnosis. Rarely, a colon malignancy is misdiagnosed as diverticulitis. Whether patients should have a colonoscopy after an episode of diverticulitis depends on the patient's history, most recent colonoscopy, and disease severity and course. In patients with a history of diverticulitis and chronic symptoms, alternative diagnoses should be excluded with both imaging and lower endoscopy. Antibiotic treatment can be used selectively rather than routinely in immunocompetent patients with mild acute uncomplicated diverticulitis. Antibiotic treatment is strongly advised in immunocompromised patients. To reduce the risk of recurrence, patients should consume a high-quality diet, have a normal body mass index, be physically active, not smoke, and avoid nonsteroidal anti-inflammatory drug use except aspirin prescribed for secondary prevention of cardiovascular disease. At the same time, patients should understand that genetic factors also contribute to diverticulitis risk. Patients should be educated that the risk of complicated diverticulitis is highest with the first presentation. An elective segmental resection should not be advised based on the number of episodes. Instead, a discussion of elective segmental resection should be personalized to consider severity of disease, patient preferences and values, as well as risks and benefits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.