Evidence map›Paper›PMID 33279367›Full record

ArticleAmerican journal of preventive medicine2021

Sex Differences in Factors Contributing to the Racial Disparity in Diabetes Risk.

April P Carson, D Leann Long, Andrea L Cherrington, Gareth R Dutton, Virginia J Howard, Todd M Brown, George Howard, Monika M Safford, Mary Cushman

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. RACIAL DISPARITIES IN STROKE AFFECTING BLACK AMERICANS.Transactions of the American Clinical and Climatological Association · 2025
    Article
  2. Article
  3. C-reactive Protein and Racial Differences in Type 2 Diabetes Incidence: The REGARDS Study.The Journal of clinical endocrinology and metabolism · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

April P CarsonDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: apcarson@uab.edu.
D Leann LongDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Andrea L CherringtonDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Gareth R DuttonDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Virginia J HowardDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Todd M BrownDivision of Cardiovascular Disease, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
George HowardDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Monika M SaffordDivision of General Internal Medicine, Weill Cornell Medical College, Cornell University, New York, New York.
Mary CushmanDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Prioritizing county-level social determinants that contribute to the greater burden of diabetes and hypertension in the USU01DP006302 · DP · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARSON, APRIL P · 2017 to 2021
$3.6M
ACL HHS U01DP006302NCCDPHP CDC HHS U01 DP006302NIDDK NIH HHS P30 DK079626NIDDK NIH HHS P30 DK111022NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

introductionDiabetes incidence differs by race in the U.S., with a persistent reported Black-White disparity. However, the factors that contribute to this excess risk in middle-aged and older adults are unclear.

methodsThis prospective cohort study included 7,171 Black and White adults aged ≥45 years without diabetes at baseline (2003‒2007) who completed a follow-up examination (2013‒2016). Modified Poisson regression was used to obtain sex-stratified RRs for diabetes. Mediation analyses using a change in β coefficient assessed individual and neighborhood factors that contribute to the racial disparity in diabetes incidence. Statistical analyses were conducted in 2018-2019.

resultsThe cumulative incidence of diabetes was higher for Black men (16.2%) and women (17.7%) than for White men (11.0%) and women (8.1%). Adjusting for age and prediabetes, diabetes risk was higher for Black women than for White women (RR=1.75, 95% CI=1.47, 2.07) and for Black men than for White men (RR=1.33, 95% CI=1.09, 1.64). The individual factors that attenuated the racial disparity the most were Southern dietary pattern (change in β=42.8%) and neighborhood socioeconomic environment (change in β=26.3%) among men and BMI (change in β=34.4%) and waist circumference (change in β=32.4%) among women. When including all factors collectively, the racial disparity in diabetes incidence was similar for men (RR=1.38, 95% CI=1.04, 1.83) and was attenuated for women (RR=1.41, 95% CI=1.11, 1.81).

conclusionsThe racial disparity in diabetes incidence remained after accounting for individual and neighborhood factors. Further investigation of additional factors underlying this racial disparity is needed to inform multilevel strategies for diabetes prevention.

Indexed as

Diabetes MellitusSex CharacteristicsAgedBlack or African AmericanFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsSex FactorsWhite People

Identifiers

PMID33279367
PMCPMC7987785

What OpenQuestion holds

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LicenceTDM
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.