Evidence map›Paper›PMID 33278068›Full record

ArticleArthritis care & research2021

Association of Medication Access Difficulty and COVID-19-Related Distress With Disease Flares in Rheumatology Patients During the COVID-19 Pandemic.

Dalynah Maldonado, Emilee Tu, Shereen N Mahmood, Dawn M Wahezi, Ruchika Darapaneni, Niloofar Sima, Laura Curiel-Duran, Lindsay M Pattison, Vilma Gabbay, Laurie J Bauman and 2 more

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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  13. Experiences of self-care during the COVID-19 pandemic among individuals with rheumatoid arthritis: A qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dalynah MaldonadoAlbert Einstein College of Medicine, Bronx, New York.ORCID 0000-0001-9872-854X
Emilee TuAlbert Einstein College of Medicine, Bronx, New York.
Shereen N MahmoodAlbert Einstein College of Medicine, Bronx, New York.
Dawn M WaheziAlbert Einstein College of Medicine and Children's Hospital at Montefiore, Bronx, New York.
Ruchika DarapaneniAlbert Einstein College of Medicine, Bronx, New York.
Niloofar SimaAlbert Einstein College of Medicine, Bronx, New York.
Laura Curiel-DuranChildren's Hospital at Montefiore, Bronx, New York.
Lindsay M PattisonAlbert Einstein College of Medicine, Bronx, New York.
Vilma GabbayAlbert Einstein College of Medicine, Bronx, New York and Nathan Kline Institute for Psychiatric Research, Orangeburg, New York.
Laurie J BaumanAlbert Einstein College of Medicine, Bronx, New York.
Anna BroderAlbert Einstein College of Medicine, Bronx, New York.ORCID 0000-0003-4772-3057
Tamar B RubinsteinAlbert Einstein College of Medicine and Children's Hospital at Montefiore, Bronx, New York.ORCID 0000-0001-8170-9377
Albert Einstein College of Medicine · USChildren's Hospital at Montefiore · USNathan Kline Institute for Psychiatric Research · US

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
The impact of hydroxychloroquine use on thrombosis and mortality in lupus-related end stage renal diseaseK23AR068441 · NIAMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BRODER, ANNA · 2017 to 2021
$832k
NCATS NIH HHS UL1 TR002556NIAMS NIH HHS K23 AR068441
6 · The paper itself

Abstract

objectiveDue to concerns of infection and medication disruptions during the COVID-19 pandemic, rheumatology patients at the pandemic epicenter were at risk of distress and poor health outcomes. We sought to investigate medication disruptions and COVID-19-related distress in the Bronx, New York shortly after the peak of the pandemic and determine whether factors related to the pandemic were associated with flares, disease activity, and overall health.

methodsIn the month following the epidemic peak, we surveyed adult patients and parents of pediatric patients from rheumatology clinics in the Bronx regarding medication access, medication interruptions, COVID-19 infection, COVID-19 hospitalization, and COVID-19-related distress. We examined which factors were associated with patient-reported flares, disease activity, and overall health scores in regression models accounting for sociodemographic characteristics and rheumatologic disease type.

resultsOf the 1,692 patients and parents of pediatric patients that were contacted, 361 (21%) responded; 16% reported medication access difficulty, 14% reported medication interruptions, and 41% reported experiencing flare(s). In a multivariable logistic regression model, medication access difficulty was associated with increased odds of flare (odds ratio [OR] 4.0 [95% confidence interval (95% CI) 1.5, 10.4]; P = 0.005), as was high COVID-19-related distress (OR 2.4 [95% CI 1.2, 4.6]; P = 0.01). In multivariable linear regression models, medication access difficulty and high COVID-19-related distress were associated with worse disease activity scores, and high COVID-19-related distress was associated with worse health scores.

conclusionMedication access difficulties and flares were common among rheumatology patients from the Bronx, New York in the month following the peak of the epidemic. Medication access difficulty and COVID-19-related distress were highly associated with flare and disease activity. COVID-19-related distress was associated with overall health scores.

Indexed as

Psychological DistressSymptom Flare UpAdultCOVID-19FemaleHealth Services AccessibilityHumansMaleMiddle AgedNew York CityRegistriesRheumatologySurveys and QuestionnairesYoung Adult

Identifiers

PMID33278068
PMCPMC8178400
OpenAlexW3108732802

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.