ArticleSkeletal radiology2021
Vertebral disk morphology of the lumbar spine: a retrospective analysis of collagen-sensitive mapping using dual-energy computed tomography.
Article in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Quantification of intervertebral disc degeneration using dual-energy computed tomography collagen maps: a comparative study with MRI Pfirrmann grading.Scientific reports · 2026Article
- Dual-energy computed tomography collagen density mapping of the temporomandibular disc.BMC medical imaging · 2025Article
- Diagnostic accuracy of dual energy computed tomography for suspected pyogenic spondylodiscitis.Scientific reports · 2025Article
- Assessment of thoracic disc degeneration using dual-energy CT-based collagen maps.European radiology experimental · 2024Article
- Visualizing patterns of intervertebral disc damage with dual-energy computed tomography: assessment of diagnostic accuracy in an ex vivo spine biophantom.Acta radiologica (Stockholm, Sweden : 1987) · 2022Article
- Future of Low-Dose Computed Tomography and Dual-Energy Computed Tomography in Axial Spondyloarthritis.Current rheumatology reports · 2022Review
- Neuroforamen stenosis remains a challenge in conventional computed tomography and new dual-energy techniques.Scientific reports · 2022Article
- Age-dependent microstructural changes of the intervertebral disc: a validation of proteoglycan-sensitive spectral CT.European radiology · 2021Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the diagnostic accuracy of collagen-sensitive maps derived from dual-energy computed tomography (DECT) for the detection of lumbar disk pathologies in a feasibility setting. MATERIALS AND
methodsWe retrospectively reviewed magnetic resonance imaging (MRI), computed tomography (CT), and DECT datasets acquired in patients who underwent periradicular therapy of the lumbar spine from June to December 2019. Three readers scored DECT collagen maps, conventional CT, and MRI for presence, type, and extent of disk pathology. Contingency table analyses were performed to determine diagnostic accuracy using MRI as standard of reference. Interrater agreement within and between imaging modalities was evaluated by computing intraclass correlation coefficients (ICCs) and Cohen's kappa. Correlation between sum scores of anteroposterior disk displacement was determined by calculation of a paired t test.
resultsIn 21 disks in 13 patients, DECT had a sensitivity of 0.87 (0.60-0.98) and specificity of 1.00 (0.54-1.00) for the detection of disk pathology. Intermodality agreement for anteroposterior disk displacement was excellent for DECT (ICC 0.963 [0.909-0.985]) and superior to CT (ICC 0.876 [0.691-0.95]). For anteroposterior disk displacement, DECT also showed greater within-modality interrater agreement (ICC 0.820 [0.666-0.916]) compared with CT (ICC 0.624 [0.39-0.808]).
conclusionOur data suggest that collagen-sensitive imaging has an added benefit, allowing more accurate evaluation of the extent of disk displacement with higher interrater reliability. Thus, DECT could provide useful diagnostic information in patients undergoing CT for other indications or with contraindications to MRI.
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