Evidence map›Paper›PMID 33277505›Full record

ArticleNature communications2020

Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy.

E I Patterson, G Elia, A Grassi, A Giordano, C Desario, M Medardo, S L Smith, E R Anderson, T Prince, G T Patterson and 14 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 274 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
274citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

274 citing papers in PubMed, 1 synthesis or guideline pooled it, 386 citations in OpenAlex.

  1. Pooled it
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  18. Ultrafast and high-throughput immunoassay assay to detect anti-SARS-CoV-2 IgG antibodies in dogs and cats.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
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214 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 3 countries.

E I PattersonCentre for Neglected Tropical Disease, Departments of Vector Biology and Tropical Disease Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0003-3465-0848
G EliaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
A GrassiI-VET srl, Laboratorio di Analisi Veterinarie, Via Ettore Majorana, 10 - 25020, Flero, BS, Italy.
A GiordanoDepartment of Veterinary Medicine, Veterinary Teaching Hospital, University of Milan, Via dell'Università 6, 26900, Lodi, Italy.
C DesarioDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
M MedardoLa Vallonèa Veterinary Diagnostic Laboratory, via G. Sirtori 9, 20017, Passirana di Rho, MI, Italy.
S L SmithInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK.
E R AndersonCentre for Neglected Tropical Disease, Departments of Vector Biology and Tropical Disease Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
T PrinceNIHR Health Protection Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, UK.
G T PattersonInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK.ORCID 0000-0001-6672-3920
E LorussoDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
M S LucenteDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
G LanaveDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
S LauziDepartment of Veterinary Medicine, Veterinary Teaching Hospital, University of Milan, Via dell'Università 6, 26900, Lodi, Italy.
U BonfantiLa Vallonèa Veterinary Diagnostic Laboratory, via G. Sirtori 9, 20017, Passirana di Rho, MI, Italy.
A StranieriDepartment of Veterinary Medicine, Veterinary Teaching Hospital, University of Milan, Via dell'Università 6, 26900, Lodi, Italy.
V MartellaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy.
F Solari BasanoArcoblu s.r.l., via Alessandro Milesi 5, 20133, Milan, Italy.
V R BarrsCity University's Jockey Club College of Veterinary Medicine and Life Sciences, 5/F, Block 1A, To Yuen Building, 31 To Yuen Street, Kowloon, Hong Kong.
A D RadfordInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK.
U AgrimiDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161, Rome, Italy.
G L HughesCentre for Neglected Tropical Disease, Departments of Vector Biology and Tropical Disease Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0002-7567-7185
S PaltrinieriDepartment of Veterinary Medicine, Veterinary Teaching Hospital, University of Milan, Via dell'Università 6, 26900, Lodi, Italy.ORCID 0000-0001-7117-7987
N DecaroDepartment of Veterinary Medicine, University of Bari Aldo Moro, Strada Prov. per Casamassima Km 3, 70010, Valenzano, BA, Italy. nicola.decaro@uniba.it.ORCID 0000-0001-6348-7969
University of Bari Aldo Moro · ITUniversity of Liverpool · GBUniversity of Milan · ITLiverpool School of Tropical Medicine · GBHong Kong Jockey Club · CNIstituto Superiore di Sanità · IT

Funding

Microbial interplay between ZIKA virus and the native microbiome in mosquitoesR21AI129507 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HUGHES, GRANT LESLIE · 2017 to 2018
$371k
Exploiting gnotobiotic systems to examine microbiota acquisition in mosquitoes and for microbiome transplantationsR21AI138074 · NIAID · TMLIVERPOOL SCHOOL OF TROPICAL MEDICINE · PI HUGHES, GRANT LESLIE · 2018 to 2019
$296k
Biotechnology and Biological Sciences Research Council BB/T001240/1Department of Health NIHR2000907NIAID NIH HHS R21 AI129507NIAID NIH HHS R21 AI138074
6 · The paper itself

Abstract

SARS-CoV-2 emerged from animals and is now easily transmitted between people. Sporadic detection of natural cases in animals alongside successful experimental infections of pets, such as cats, ferrets and dogs, raises questions about the susceptibility of animals under natural conditions of pet ownership. Here, we report a large-scale study to assess SARS-CoV-2 infection in 919 companion animals living in northern Italy, sampled at a time of frequent human infection. No animals tested PCR positive. However, 3.3% of dogs and 5.8% of cats had measurable SARS-CoV-2 neutralizing antibody titers, with dogs from COVID-19 positive households being significantly more likely to test positive than those from COVID-19 negative households. Understanding risk factors associated with this and their potential to infect other species requires urgent investigation.

Indexed as

Adaptive ImmunityAnimalsAntibodies, NeutralizingAntibodies, ViralCatsCOVID-19DogsHumansItalyAntibodies, NeutralizingAntibodies, Viral

Identifiers

PMID33277505
PMCPMC7718263
OpenAlexW3107669892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.