ArticleNature communications2020
3D projection electrophoresis for single-cell immunoblotting.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Molecular profiling of the single-cell proteome via gel electrophoresis and 3D single-molecule imaging.Nature communications · 2026Article
- Single-Cell Protein Assays in Context: From 2D to 3D and In Situ Analysis.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026Review
- Electromigration of Charged Analytes Through Immiscible Fluids in Multiphasic Electrophoresis.Electrophoresis · 2025Article
- DropBlot: single-cell western blotting of chemically fixed cancer cells.Nature communications · 2024Article
- Electromigration of Charged Analytes Through Immiscible Fluids in Multiphasic Electrophoresis.bioRxiv : the preprint server for biology · 2024Article
- Deciphering cellular complexity: advances and future directions in single-cell protein analysis.Frontiers in bioengineering and biotechnology · 2024Review
- [Advances in microchip electrophoresis for the separation and analysis of biological samples].Se pu = Chinese journal of chromatography · 2023Review
- Three-dimensional histological electrophoresis enables fast automatic distinguishment of cancer margins and lymph node metastases.Science advances · 2023Article
- Past, current, and future roles of 3D printing in the development of capillary electrophoresis systems.Trends in analytical chemistry : TRAC · 2023Article
- An integrated Mg battery-powered iontophoresis patch for efficient and controllable transdermal drug delivery.Nature communications · 2023Article
- The Intriguing Landscape of Single-Cell Protein Analysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Electrotransfer of Immunoprobes through Thin-Layer Polyacrylamide Gels.Analytical chemistry · 2022Article
- Multimodal detection of protein isoforms and nucleic acids from mouse pre-implantation embryos.Nature protocols · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Immunoassays and mass spectrometry are powerful single-cell protein analysis tools; however, interfacing and throughput bottlenecks remain. Here, we introduce three-dimensional single-cell immunoblots to detect both cytosolic and nuclear proteins. The 3D microfluidic device is a photoactive polyacrylamide gel with a microwell array-patterned face (xy) for cell isolation and lysis. Single-cell lysate in each microwell is "electrophoretically projected" into the 3
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.