ArticleBMJ open2020
Adiposity change and mortality in middle-aged to older Chinese: an 8-year follow-up of the Guangzhou Biobank Cohort Study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Associations of obesity indices change with cardiovascular outcomes: a dose-response meta-analysis.International journal of obesity (2005) · 2024Pooled it
- Analysis of Changes in Weight, Waist Circumference, or Both, and All-Cause Mortality in Chinese Adults.JAMA network open · 2022Pooled it
- Associations of Change in Body Size With All-Cause and Cause-Specific Mortality Among Healthy Older Adults.JAMA network open · 2023Trial
- Associations of changes in waist-to-height ratio with all-cause mortality among Chinese older adults: a national cohort study.Frontiers in nutrition · 2026Article
- Changes in Weight, Waist Circumference or Both With Incident Heart Failure in Chinese Middle-Aged and Older Adults.Journal of cachexia, sarcopenia and muscle · 2025Article
- Article
- Association of weight change with all-cause and cause-specific mortality: an age-stratified analysis.BMC medicine · 2024Article
- Association of adverse childhood experiences with anemia in older Chinese: Guangzhou Biobank Cohort Study.Scientific reports · 2024Article
- Long-term waist circumference trajectories and body mass index with all-cause mortality in older Chinese adults: a prospective nationwide cohort study.Archives of public health = Archives belges de sante publique · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the associations of change in body mass index (BMI) and waist circumference (WC) over an average of 4 years with subsequent mortality risk in middle-aged to older Chinese.
designProspective cohort study based on the Guangzhou Biobank Cohort Study.
settingCommunity-based sample.
participants17 773 participants (12 956 women and 4817 men) aged 50+ years. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome measure was all-cause mortality. Secondary outcome measures were cardiovascular disease (CVD) and cancer mortality. Causes of death were obtained via record linkage, and coded according to the International Classification of Diseases (tenth revision).
results1424 deaths (53.4% women) occurred in the 17 773 participants (mean age 61.2, SD 6.8 years) during an average follow-up of 7.8 (SD=1.5) years, and 97.7% of participants did not have an intention of weight loss . Compared with participants with stable BMI, participants with BMI loss (>5%), but not gain, had a higher risk of all-cause mortality (HR=1.49, 95% CI 1.31 to 1.71), which was greatest in those who were underweight (HR=2.45, 95% CI 1.31 to 4.59). Similar patterns were found for WC. In contrast, for participants with a BMI of ≥27.5 kg/m
conclusionIn older people, unintentional BMI/WC loss, especially in those who were underweight was associated with higher mortality risk. However, BMI gain in those with obesity showed excess risks of all-cause and cancer mortality, but not CVD mortality. Frequent monitoring of changes in body size can be used as an early warning for timely clinical investigations and interventions and is important to inform appropriate health management in older Chinese.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.