Evidence map›Paper›PMID 33276701›Full record

ArticleBiointerphases2020

Evaluation of surface layer stability of surface-modified polyester biomaterials.

Hamish Poli, Alexandra L Mutch, Anitha A, Saso Ivanovski, Cedryck Vaquette, David G Castner, María Natividad Gómez-Cerezo, Lisbeth Grøndahl

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biointerphases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Hamish PoliSchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia 4072, Australia.ORCID 0000000235461830
Alexandra L MutchSchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia 4072, Australia.ORCID 0000000290109047
Anitha ASchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia 4072, Australia.ORCID 000000030964741X
Saso IvanovskiSchool of Dentistry, The University of Queensland, Herston 4006, Australia.ORCID 0000000153390936
Cedryck VaquetteSchool of Dentistry, The University of Queensland, Herston 4006, Australia.ORCID 0000000179374432
David G CastnerDepartment of Bioengineering and Department of Chemical Engineering, National ESCA and Surface Analysis Center for Biomedical Problems, University of Washington, Seattle, Washington 98195.
María Natividad Gómez-CerezoSchool of Dentistry, The University of Queensland, Herston 4006, Australia.ORCID 0000000197081000
Lisbeth GrøndahlSchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia 4072, Australia.ORCID 0000000160129808
The University of Queensland · AU

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G · 2003 to 2019
$17.6M
NIBIB NIH HHS P41 EB002027
6 · The paper itself

Abstract

Surface modification of biomaterials is a strategy used to improve cellular and in vivo outcomes. However, most studies do not evaluate the lifetime of the introduced surface layer, which is an important aspect affecting how a biomaterial will interact with a cellular environment both in the short and in the long term. This study evaluated the surface layer stability in vitro in buffer solution of materials produced from poly(lactic-co-glycolic acid) (50:50) and polycaprolactone modified by hydrolysis and/or grafting of hydrophilic polymers using grafting from approaches. The data presented in this study highlight the shortcomings of using model substrates (e.g., spun-coated films) rather than disks, particles, and scaffolds. It also illustrates how similar surface modification strategies in some cases result in very different lifetimes of the surface layer, thus emphasizing the need for these studies as analogies cannot always be drawn.

Indexed as

Biocompatible MaterialsHydrolysisHydrophobic and Hydrophilic InteractionsPhotoelectron SpectroscopyPolyestersPolylactic Acid-Polyglycolic Acid CopolymerSurface PropertiesBiocompatible MaterialsPolyestersPolylactic Acid-Polyglycolic Acid Copolymer

Identifiers

PMID33276701
PMCPMC7719048
OpenAlexW3109863706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.