Evidence map›Paper›PMID 33276667›Full record

ArticleJournal of clinical medicine2020

Urine High-Sensitivity Troponin I Predict Incident Cardiovascular Events in Patients with Diabetes Mellitus.

Ju-Yi Chen, Shuenn-Yuh Lee, Yi-Heng Li, Chia-Yu Lin, Meng-Dar Shieh, Ding-Siang Ciou

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Cardiotoxicity as a Possible Side Effect of Statins.Reviews in cardiovascular medicine · 2023
    Review
  11. Review of Recent Laboratory and Experimental Data on Cardiotoxicity of Statins.Journal of cardiovascular development and disease · 2022
    Review
  12. Review
  13. Review
  14. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ju-Yi ChenDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0003-2760-9978
Shuenn-Yuh LeeDepartment of Electrical Engineering, National Cheng-Kung University, Tainan 704, Taiwan.ORCID 0000-0002-9757-1410
Yi-Heng LiDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Chia-Yu LinDepartment of Chemical Engineering, National Cheng-Kung University, Tainan 704, Taiwan.
Meng-Dar ShiehDepartment of Industrial Design, National Cheng-Kung University, Tainan 704, Taiwan.
Ding-Siang CiouDepartment of Electrical Engineering, National Cheng-Kung University, Tainan 704, Taiwan.

Funding

Ministry of Science and Technology, Taiwan MOST 107-2218-E-006-033, 108-2218-E-006-019, 109-2218-E-006-024
6 · The paper itself

Abstract

In patients with diabetes mellitus (DM), incident cardiovascular (CV) events are associated with poor long-term outcomes. Serum high-sensitivity troponin I (hs-TnI) is widely used to diagnose and predict outcomes in patients with acute coronary syndrome, however, few studies have investigated the accuracy of urine hs-TnI as a predictor for incident CV events in patients with DM. The enrolled participants included patients with DM. Fresh urine hs-TnI levels were measured. Medical records of enrolled patients were used to determine the number of incident CV events prospectively for 3 months. The study cohort comprised 378 participants. We observed significantly higher levels of urine hs-TnI in those with than without subsequent incident CV events. The multivariate logistic regression analysis using different models consistently showed that urine hs-TnI > 4.10 pg/mL was an independent factor predictive of incident CV events. The ROC-AUC analysis revealed that the optimal cutoff value for urine hs-TnI for predicting incident CV events was 1.55 pg/mL and the area was 0.611 (

Indexed as

diabetes mellitusincident cardiovascular eventstroponinurine

Identifiers

PMID33276667
PMCPMC7761585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.