Evidence map›Paper›PMID 33276664›Full record

ArticleInternational journal of environmental research and public health2020

Serum Gamma Glutamyltransferase Is Associated with 25-Hydroxyvitamin D Status in Elderly Patients with Stable Coronary Artery Disease.

Aleksander Danikiewicz, Bartosz Hudzik, Justyna Nowak, Joanna Kowalska, Iwona Zieleń-Zynek, Janusz Szkodzinski, Han Naung Tun, Barbara Zubelewicz-Szkodzinska

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aleksander DanikiewiczDepartment of Nutrition Related Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.ORCID 0000-0002-1867-1326
Bartosz HudzikDepartment of Cardiovascular Disease Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.ORCID 0000-0003-3880-5325
Justyna NowakDepartment of Cardiovascular Disease Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.
Joanna KowalskaDepartment of Nutrition Related Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.
Iwona Zieleń-ZynekDepartment of Nutrition Related Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.
Janusz SzkodzinskiThird Department of Cardiology, Silesian Center for Heart Disease, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.
Han Naung TunResearch and Clinical Working Groups, European Society of Cardiology, 06-903 Sophia Antipolis, France.
Barbara Zubelewicz-SzkodzinskaDepartment of Nutrition Related Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, 41-900 Bytom, Poland.ORCID 0000-0002-8670-8581
Medical University of Silesia · PLEuropean Society of Cardiology · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo previous study has investigated the association between gamma glutamyltransferase (GGT) and vitamin D in patients with stable coronary artery disease (CAD). We investigated the cross-sectional associations between vitamin D status as assessed by serum 25(OH)D and GGT.

methods169 patients were enrolled. Study population was divided into three groups: 1: 25(OH)D < 10 ng/mL (

resultsGGT activity was the highest in vitamin D severely deficient patients and the lowest in vitamin D insufficient patients. GGT was inversely correlated with 25(OH)D concentrations (R = -0.23;

conclusionsWe identified an interaction between declining 25(OH)D levels and rising GGT levels with increasing age, which resulted in an unfavorable 25(OH)D-to-GGT ratio in stable CAD patients. These results suggest that these changes might further contribute to a high cardiovascular risk in the elderly.

Indexed as

AgedCoronary Artery DiseaseCross-Sectional Studiesgamma-GlutamyltransferaseHumansMaleVitamin DVitamin D Deficiency25-hydroxyvitamin Dgamma-GlutamyltransferaseVitamin D25(OH)Dcoronary artery diseasegamma glutamyltransferasevitamin D

Identifiers

PMID33276664
PMCPMC7729888
OpenAlexW3107936976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.