ReviewJournal of clinical medicine2020
Bio-Inspired Systems in Nonsurgical Periodontal Therapy to Reduce Contaminated Aerosol during COVID-19: A Comprehensive and Bibliometric Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Periodontal Disease Elevates IL-6 Levels During Initial Symptoms of COVID-19.Diagnostics (Basel, Switzerland) · 2025Article
- Differences Between Two Devices With Function of Periopolishing and Piezoelectric Scaler: A Randomized Clinical Trial.International journal of dentistry · 2025Article
- The Home Use of Probiotics and Paraprobiotics for the Maintenance of Tongue Eubiosis: A Case Report.Case reports in dentistry · 2025Article
- Standardization of the protocol for oral cavity examination and collecting of the biological samples for microbiome research using the next-generation sequencing (NGS): own experience with the COVID-19 patients.Scientific reports · 2024Article
- Oral Myco- and Bacteriobiota and Yeast Infections in Mechanically Ventilated COVID-19 Patients.Microorganisms · 2023Article
- Personalized Treatment of Periodontitis in a Patient with McArdle's Disease: The Benefits from Probiotics.Case reports in dentistry · 2023Article
- Epidemiological evaluation of patient compliance regarding oral health and hygiene during the COVID-19 period.Einstein (Sao Paulo, Brazil) · 2023Article
- Oral Changes in Hospitalized COVID-19 Patients: A Cross-Sectional Multicentric Study.International journal of dentistry · 2023Article
- Characterization of Ag-Ion Releasing Zeolite Filled 3D Printed Resins.Journal of functional biomaterials · 2022Article
- COVID-19 Related Information on Pediatric Dental Care including the Use of Teledentistry: A Narrative Review.Children (Basel, Switzerland) · 2022Review
- Oral Manifestations of COVID-19: A Cross-Sectional Study of Their Prevalence and Association with Disease Severity.Journal of clinical medicine · 2022Article
- Host Microbiota Balance in Teenagers with Gum Hypertrophy Concomitant with Acne Vulgaris: Role of Oral Hygiene Associated with Topical Probiotics.Microorganisms · 2022Article
- Dental Care and Education Facing Highly Transmissible SARS-CoV-2 Variants: Prospective Biosafety Setting: Prospective, Single-Arm, Single-Center Study.International journal of environmental research and public health · 2022Article
- Evaluation of Adjuvant Systems in Non-Surgical Peri-Implant Treatment: A Literature Review.Healthcare (Basel, Switzerland) · 2022Review
- The Impact of the COVID-19 Pandemic on Dentistry and Dental Education: A Narrative Review.International journal of environmental research and public health · 2022Review
- Knowledge of COVID-19 Infection Guidelines among the Dental Health Care Professionals of Jazan Region, Saudi Arabia.International journal of environmental research and public health · 2022Article
- Assessment of Oral Microbiome Changes in Healthy and COVID-19-Affected Pregnant Women: A Narrative Review.Microorganisms · 2021Review
- Dispersion of Aerosols Generated during Dental Therapy.International journal of environmental research and public health · 2021Review
- COVID-19 and periodontitis: reflecting on a possible association.Head & face medicine · 2021Review
- Impact of COVID-19 on the Dental Community: Part I before Vaccine (BV).Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOn 30 January 2020, a public health emergency of international concern was declared as a result of the new COVID-19 disease, caused by the SARS-CoV-2 virus. This virus is transmitted by air and, therefore, clinical practices with the production of contaminant aerosols are highly at risk. The purpose of this review was to assess the effectiveness of bio-inspired systems, as adjuvants to nonsurgical periodontal therapy, in order to formulate bio-inspired protocols aimed at restoring optimal condition, reducing bacteremia and aerosols generation.
methodsA comprehensive and bibliometric review of articles published in English. Research of clinical trials (RCTs) were included with participants with chronic or aggressive periodontal disease, that have compared benefits for nonsurgical periodontal therapy (NSPT).
resultsSeventy-four articles have been included. For probing depth (PPD) there was a statically significant improvement in laser, probiotic, chlorhexidine groups, such as gain in clinical attachment level (CAL). Bleeding on probing (BOP) reduction was statistically significant only for probiotic and chlorhexidine groups. There were changes in microbiological and immunological parameters.
conclusionsThe use of bio-inspired systems in nonsurgical periodontal treatment may be useful in reducing risk of bacteremia and aerosol generation, improving clinical, microbiological and immunological parameters, of fundamental importance in a context of global pandemic, where the reduction of bacterial load in aerosols becomes a pivotal point of clinical practice, but other clinical trials are necessary to achieve statistical validity.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.