Evidence map›Paper›PMID 33276596›Full record

ArticleVaccines2020

Cellular Immune Responses in Rainbow Trout (

Kimberly A Veenstra, Kjartan Hodneland, Susanne Fischer, Kota Takehana, Rodrigo Belmonte, Uwe Fischer

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in immunology · 2026
    Article
  4. Pathogens (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Kimberly A VeenstraFriedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Infectology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.
Kjartan HodnelandMSD Animal Health Innovation, Thormøhlens Gate 55, 5006 Bergen, Norway.
Susanne FischerFriedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Infectology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.
Kota TakehanaNagano Prefectural Fisheries Experimental Station, 2871 Oaza-Nakagawate, Akashina, Azumino-shi, Nagano 399-7102, Japan.
Rodrigo BelmonteMSD Animal Health Innovation, Thormøhlens Gate 55, 5006 Bergen, Norway.
Uwe FischerFriedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Infectology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.
Friedrich-Loeffler-Institut · DEMSD (Norway) · NOGunma Prefectural Fisheries Experimental Station · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral disease outbreaks remain a significant limiting factor for aquaculture. The majority of licensed vaccines used in the industry are administered as oil-adjuvanted formulations carrying inactivated whole pathogens. Cell-mediated immune responses, in particular those based on virus-specific cytotoxic T-cells (CTLs) to conventional inactivated oil-based vaccines, are largely unexplored. As vaccines cannot be optimized against viral pathogens if knowledge of host cellular immune mechanisms remains unknown, in this study we examined fundamental cell-mediated immune responses after vaccination of rainbow trout with an oil-adjuvanted inactivated vaccine against salmonid alphavirus (SAV) and after infection with SAV. A unique

Indexed as

adjuvantcell-mediated immune responsecytotoxicityELISAgene expressionpancreas diseaserainbow troutsalmonid alphavirus (SAV)vaccine

Identifiers

PMID33276596
PMCPMC7761581
OpenAlexW3107888457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.