ReviewMarine drugs2020
Progress in Research on Bioactive Secondary Metabolites from Deep-Sea Derived Microorganisms.
Review in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Cytochalasins are a fascinating class of natural compounds: advances in the chemistry, biological activities, mode of action, and structure-activity relationships of novel cytochalasins isolated in the last decade are described.Natural products and bioprospecting · 2026Review
- Deep-sea Microbial Dataset of the Antarctic Ocean (dsMDAO): A high-resolution deep-sea microbial dataset of the Antarctic Ocean reveals potential for taxonomic and functional diversity.Microbial genomics · 2026Article
- Isolation and Characterisation of Alkaloids from Marine-DerivedMarine drugs · 2026Article
- Global distribution of deep-sea natural products shows environmental and phylogenetic undersampling with potential for biodiscovery.Scientific reports · 2026Article
- New Cytotoxic Anthraquinone Derivatives from a Deep-Sea-DerivedMarine drugs · 2026Article
- Multi-Omic Assessment of Microbial Communities and Their Polyketide Biosynthetic Potential Across Abyssal Sediments.Environmental microbiology · 2026Article
- Lubrication Challenges in Deep-Sea Gear Trans-Missions: A Review of High-Pressure and Low-Temperature Effects.Materials (Basel, Switzerland) · 2026Review
- Article
- Truncated Equinin B Variants Reveal the Sequence Determinants of Antimicrobial Selectivity.Marine drugs · 2026Article
- Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistantMycology · 2026Review
- Unlocking potent anti-tuberculosis natural products through structure-activity relationship analysis.Natural products and bioprospecting · 2025Review
- Strategies Used for the Discovery of New Microbial Metabolites with Antibiotic Activity.Molecules (Basel, Switzerland) · 2025Review
- Novel and diverse features identified in the genomes of bacteria isolated from a hydrothermal vent plume.Applied and environmental microbiology · 2025Article
- Antioxidant and Anti-Inflammatory Activities of Cutlassfish Head Peptone in RAW 264.7 Macrophages.Antioxidants (Basel, Switzerland) · 2025Article
- Metabolic Blockade-Based Genome Mining ofMarine drugs · 2025Article
- From the depths of the Java Trench: genomic analysis of Priestia flexa JT4 reveals bioprospecting and lycopene production potential.BMC genomics · 2024Article
- Anthoteibinenes A-E from the Irish Deep-Sea CoralOrganic letters · 2024Article
- Recent Advances in Anti-Inflammatory Compounds from Marine Microorganisms.Marine drugs · 2024Review
- Immunomodulatory Compounds from the Sea: From the Origins to a Modern Marine Pharmacopoeia.Marine drugs · 2024Review
- The Plethora of Microbes with Anti-Inflammatory Activities.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Deep sea has an extreme environment which leads to biodiversity of microorganisms and their unique physical and biochemical mechanisms. Deep-sea derived microorganisms are more likely to produce novel bioactive substances with special mechanism of action for drug discovery. This article reviews secondary metabolites with biological activities such as anti-tumor, anti-bacterial, anti-viral, and anti-inflammatory isolated from deep-sea fungi and bacteria during 2018-2020. Effective methods for screening and obtaining natural active compounds from deep-sea microorganisms are also summarized, including optimizing the culture conditions, using genome mining technology, biosynthesis and so on. The comprehensive application of these methods makes broader prospects for the development and application of deep sea microbial bioactive substances.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.