Evidence map›Paper›PMID 33276562›Full record

ReviewCancers2020

Ablative Radiotherapy in Prostate Cancer: Stereotactic Body Radiotherapy and High Dose Rate Brachytherapy.

Ting Martin Ma, Oscar Lilleby, Wolfgang A Lilleby, Amar U Kishan

Abstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ting Martin MaDepartment of Radiation Oncology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-0053-7874
Oscar LillebyFaculty of Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Wolfgang A LillebyDepartment of Oncology, Oslo University Hospital, 0424 Oslo, Norway.ORCID 0000-0002-8390-9353
Amar U KishanDepartment of Radiation Oncology, University of California, Los Angeles, CA 90095, USA.

Funding

American Society of Radiation Oncology n/aProstate Cancer Foundation n/a
6 · The paper itself

Abstract

Prostate cancer (PCa) is the most common noncutaneous solid organ malignancy among men worldwide. Radiation therapy is a standard of care treatment option that has historically been delivered in the form of small daily doses of radiation over the span of multiple weeks. PCa appears to have a unique sensitivity to higher doses of radiation per fraction, rendering it susceptible to abbreviated forms of treatment. Stereotactic body radiation therapy (SBRT) and high-dose-rate brachytherapy (HDRBT) are both modern radiation modalities that allow the precise delivery of ablative doses of radiation to the prostate while maximally sparing sensitive surrounding normal structures. In this review, we highlight the evidence regarding the radiobiology, oncological outcomes, toxicity and dose/fractionation schemes of SBRT and HDRBT monotherapy in men with low-and intermediate-risk PCa.

Indexed as

ablative radiotherapybiochemical recurrent free survival (bRFS)high-dose-rate brachytherapy (HDRBT)prostate cancerstereotactic body radiotherapy (SBRT)toxicity

Identifiers

PMID33276562
PMCPMC7761604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.