Evidence map›Paper›PMID 33276541›Full record

ArticlePathogens (Basel, Switzerland)2020

Development of an In Vitro Membrane Model to Study the Function of EsxAB Heterodimer and Establish the Role of EsxB in Membrane Permeabilizing Activity of

Salvador Vazquez Reyes, Supriyo Ray, Javier Aguilera, Jianjun Sun

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Secreted proteins ofFrontiers in tuberculosis · 2026
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Salvador Vazquez ReyesDepartment of Biological Sciences, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Supriyo RayDepartment of Chemistry & Biochemistry, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Javier AguileraDepartment of Biological Sciences, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Jianjun SunDepartment of Biological Sciences, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
The University of Texas at El Paso · USBowie State University · US

Funding

TOXICOLOGY PROJECTG12RR008124 · NCRR · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 1992 to 2011
$20.8M
Receptor disulfide allosteric regulation of anthrax toxin actionSC1GM095475 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI SUN, JIANJUN · 2011 to 2020
$2.6M
NCRR NIH HHS 5G12RR008124NIGMS NIH HHS SC1 GM095475NIGMS NIH HHS SC1GM095475
6 · The paper itself

Abstract

EsxA and EsxB are secreted as a heterodimer and have been shown to play critical roles in phagosome rupture and translocation of

Indexed as

CFP-10ESAT-6EsxAEsxBmembrane permeabilizing activityMycobacterium tuberculosis

Identifiers

PMID33276541
PMCPMC7761419
OpenAlexW3107530817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.