Evidence map›Paper›PMID 33276526›Full record

ArticlePathogens (Basel, Switzerland)2020

Design and Characterization of a Novel Tool for the Antigenic Enrichment of

Fabio Antenucci, Armen Ovsepian, Agnieszka Wrobel, Hanne Cecilie Winther-Larsen, Anders Miki Bojesen

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Frontiers in veterinary science · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Fabio AntenucciDepartment of Veterinary and Animal Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Copenhagen, Denmark.ORCID 0000-0003-0515-3746
Armen OvsepianDepartment of Veterinary and Animal Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Copenhagen, Denmark.ORCID 0000-0001-5472-3747
Agnieszka WrobelSection of Pharmaceutical Biosciences, Centre of Integrative Microbial Evolution, Department of Pharmacy, University of Oslo, Sem Sælandsvei 3, 0316 Oslo, Norway.
Hanne Cecilie Winther-LarsenSection of Pharmaceutical Biosciences, Centre of Integrative Microbial Evolution, Department of Pharmacy, University of Oslo, Sem Sælandsvei 3, 0316 Oslo, Norway.
Anders Miki BojesenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Copenhagen, Denmark.ORCID 0000-0003-4030-0019
University of Copenhagen · DKUniversity of Oslo · NO

Funding

Center for Control of Antimicrobial Resistance (UC-Care) Grant number not applicableCenter for Research in Pig Production and Health (CPH Pig) at University of Copenhagen Grant number not applicableKøbenhavns Universitet Grant number not applicable
6 · The paper itself

Abstract

Production and isolation of recombinant proteins are costly and work-intensive processes, especially in immunology when tens or hundreds of potential immunogens need to be purified for testing. Here we propose an alternative method for fast screening of immunogen candidates, based on genetic engineering of recombinant bacterial strains able to express and expose selected antigens on their outer membrane. In

Indexed as

Actinobacillus pleuropneumoniaeantigenic enrichmentimmunogen screeningvaccine development

Identifiers

PMID33276526
PMCPMC7761619
OpenAlexW3109013230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.