Evidence map›Paper›PMID 33276436›Full record

ArticlePharmaceutics2020

Physicochemical and Biological Performance of Aloe Vera-Incorporated Native Collagen Films.

Mireia Andonegi, Ainhoa Irastorza, Ander Izeta, Koro de la Caba, Pedro Guerrero

Abstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Biocompatible Thin Films Deposited by Laser Techniques.Materials (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Green Synthesized Polymeric Iodophors with Thyme as Antimicrobial Agents.International journal of molecular sciences · 2024
    Article
  6. Polymers · 2024
    Article
  7. Effect ofFood science & nutrition · 2023
    Article
  8. Article
  9. A New Biomaterial Derived fromPharmaceutics · 2023
    Review
  10. High-ContentPolymers · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mireia AndonegiBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0001-7250-3051
Ainhoa IrastorzaTissue Engineering Group, Biodonostia Health Research Institute, Paseo Doctor Begiristain s/n, 20014 Donostia-San Sebastián, Spain.ORCID 0000-0002-1091-8654
Ander IzetaTissue Engineering Group, Biodonostia Health Research Institute, Paseo Doctor Begiristain s/n, 20014 Donostia-San Sebastián, Spain.ORCID 0000-0003-1879-7401
Koro de la CabaBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-8866-7314
Pedro GuerreroBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-9785-7048

Funding

Eusko Jaurlaritza KK-2019/00006Eusko Jaurlaritza PRE_2017_1_0025Eusko Jaurlaritza PRE_2019_1_0031
6 · The paper itself

Abstract

Collagen was obtained from porcine skin by mechanical pretreatments with the aim of preserving the triple helix structure of native collagen, which was indirectly corroborated by differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) results. Moreover, aloe vera (AV), with inherent biological properties, was incorporated into collagen film formulations, and films were prepared by compression and characterized to assess their suitability for biomedical applications. SEM images showed that the fibrillar structure of collagen changed to a rougher structure with the addition of AV, in accordance with the decrease in the lateral packaging of collagen chains observed by XRD analysis. These results suggested interactions between collagen and AV, as observed by FTIR. Considering that AV content higher than 20 wt % did not promote further interactions, this formulation was employed for biological assays and the suitability of AV/collagen films developed for biomedical applications was confirmed.

Indexed as

aloe verabiomaterialsfilmsnative collagen

Identifiers

PMID33276436
PMCPMC7760042

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.