Evidence map›Paper›PMID 33276425›Full record

ArticleInternational journal of molecular sciences2020

Miriam Saponaro, Isabella Giacomini, Giulia Morandin, Veronica Cocetta, Eugenio Ragazzi, Genny Orso, Ilaria Carnevali, Massimiliano Berretta, Mariangela Mancini, Francesco Pagano and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

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  10. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  11. Effects of a proprietary mixture of extracts fromFrontiers in pharmacology · 2024
    Article
  12. Review
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  14. Review
  15. Review
  16. Article
  17. Review
  18. Anticancer Effects of Urtica Dioica in Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Miriam SaponaroDepartment of Medicine, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-9647-8011
Isabella GiacominiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.ORCID 0000-0002-7154-7930
Giulia MorandinDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.
Veronica CocettaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.ORCID 0000-0002-0350-8403
Eugenio RagazziDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.ORCID 0000-0002-0390-6823
Genny OrsoDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.
Ilaria CarnevaliClinical Research Department of Schwabe Pharma Italia, 39100 Bolzano, Italy.
Massimiliano BerrettaDepartment of Medical Oncology-Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy.ORCID 0000-0002-9837-9148
Mariangela ManciniUrological Clinic, Department of Surgical, Oncological and Gastroenterological Sciences and School of Medicine and Surgery, University of Padova, 35124 Padova, Italy.ORCID 0000-0001-6766-8767
Francesco PaganoVeneto Institute of Molecular Medicine, 35129 Padova, Italy.
Monica MontopoliVeneto Institute of Molecular Medicine, 35129 Padova, Italy.ORCID 0000-0001-6182-4132
University of Padua · ITCentro di Riferimento Oncologico · ITVeneto Institute of Molecular Medicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) is an age-related chronic disorder, characterized by the hyperproliferation of prostatic epithelial and stromal cells, which drives prostate enlargement. Since BPH aetiology and progression have been associated with the persistence of an inflammatory stimulus, induced both by Nuclear Factor-kappa B (NF-κB) activation and reactive oxygen species (ROS) production, the inhibition of these pathways could result in a good tool for its clinical treatment. This study aimed to evaluate the antioxidant and anti-inflammatory activity of a combined formulation of

Indexed as

Anti-Inflammatory AgentsCell LineCell ProliferationDose-Response Relationship, DrugHumansMalePlant ExtractsProstatic HyperplasiaSerenoaUrtica dioicaAnti-Inflammatory AgentsPlant Extractssaw palmetto extractBPHinflammationoxidative stressSerenoa repensUrtica dioica

Identifiers

PMID33276425
PMCPMC7730996
OpenAlexW3108970572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.