Evidence map›Paper›PMID 33275948›Full record

ArticleThe Lancet. Global health2021

Potential impact of midwives in preventing and reducing maternal and neonatal mortality and stillbirths: a Lives Saved Tool modelling study.

Andrea Nove, Ingrid K Friberg, Luc de Bernis, Fran McConville, Allisyn C Moran, Maria Najjemba, Petra Ten Hoope-Bender, Sally Tracy, Caroline S E Homer

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The Lancet. Global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05237375 (MIDWIZE - Strengthening Midwives to Implement and Sustain Quality Improvements to Optimise Maternity Care), which is not on this map. Cited by 187 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed, 5 pooled it
53.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05237375 unknown statusnot on this mapstarted 2022, after this paper: background citation

MIDWIZE - Strengthening Midwives to Implement and Sustain Quality Improvements to Optimise Maternity Care: A Longitudinal Observational Study in Uganda

TypeobservationalSponsorKarolinska InstitutetRan2022 to 2025Enrolled1,000ConditionsMidwiferyArmsThe MIDWIZE model
3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 5 syntheses or guidelines pooled it, 372 citations in OpenAlex.

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  11. [Joint trajectories and evolution patterns of direct and indirect maternal mortality across 204 countries from 2000 to 2021].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Andrea NoveNovametrics, Duffield, UK. Electronic address: andrea@novametrics.org.
Ingrid K FribergTacoma, WA, USA.
Luc de BernisBias, France.
Fran McConvilleDepartment of Maternal, Newborn, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland.
Allisyn C MoranDepartment of Maternal, Newborn, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland.
Maria NajjembaUganda Country Office, United Nations Population Fund, Kampala, Uganda.
Petra Ten Hoope-BenderUnited Nations Population Fund Office of Geneva, Geneva, Switzerland.
Sally TracyFaculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Caroline S E HomerMaternal, Child and Adolescent Health, Burnet Institute, Melbourne, VIC, Australia.
World Health Organization · CHBurnet Institute · AUUniversity of Sydney · AUWorld Health Organization - Uganda · UG

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundStrengthening the capacity of midwives to deliver high-quality maternal and newborn health services has been highlighted as a priority by global health organisations. To support low-income and middle-income countries (LMICs) in their decisions about investments in health, we aimed to estimate the potential impact of midwives on reducing maternal and neonatal deaths and stillbirths under several intervention coverage scenarios.

methodsFor this modelling study, we used the Lives Saved Tool to estimate the number of deaths that would be averted by 2035, if coverage of health interventions that can be delivered by professional midwives were scaled up in 88 countries that account for the vast majority of the world's maternal and neonatal deaths and stillbirths. We used four scenarios to assess the effects of increasing the coverage of midwife-delivered interventions by a modest amount (10% every 5 years), a substantial amount (25% every 5 years), and the amount needed to reach universal coverage of these interventions (ie, to 95%); and the effects of coverage attrition (a 2% decrease every 5 years). We grouped countries in three equal-sized groups according to their Human Development Index. Group A included the 30 countries with the lowest HDI, group B included 29 low-to-medium HDI countries, and group C included 29 medium-to-high HDI countries.

findingsWe estimated that, relative to current coverage, a substantial increase in coverage of midwife-delivered interventions could avert 41% of maternal deaths, 39% of neonatal deaths, and 26% of stillbirths, equating to 2·2 million deaths averted per year by 2035. Even a modest increase in coverage of midwife-delivered interventions could avert 22% of maternal deaths, 23% of neonatal deaths, and 14% of stillbirths, equating to 1·3 million deaths averted per year by 2035. Relative to current coverage, universal coverage of midwife-delivered interventions would avert 67% of maternal deaths, 64% of neonatal deaths, and 65% of stillbirths, allowing 4·3 million lives to be saved annually by 2035. These deaths averted would be particularly concentrated in the group B countries, which currently account for a large proportion of the world's population and have high mortality rates compared with group C.

interpretationMidwives can help to substantially reduce maternal and neonatal mortality and stillbirths in LMICs. However, to realise this potential, midwives need to have skills and competencies in line with recommendations from the International Confederation of Midwives, to be part of a team of sufficient size and skill, and to work in an enabling environment. Our study highlights the potential of midwives but there are many challenges to the achievement of this potential. If increased coverage of midwife-delivered interventions can be achieved, health systems will be better able to provide effective coverage of essential sexual, reproductive, maternal, newborn, and adolescent health interventions.

fundingNew Venture Fund.

Indexed as

Infant MortalityMaternal MortalityDeveloping CountriesFemaleHumansInfantInfant, NewbornMaternal Health ServicesMidwiferyModels, StatisticalStillbirth

Identifiers

PMID33275948
PMCPMC7758876
OpenAlexW3107383487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.