ArticleLancet (London, England)2021
Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019.
Article in Lancet (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 13 registered trials, which are not on this map. Cited by 1,265 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Manual Therapy to the Cervical Spine and Diaphragm,Combined With Breathing Reeducation Exercises, in Patients With Non-specific Chronic Neck Pain: A Randomized Controlled Trial
Digitally Delivered Exercise and Education Treatment for Shoulder Pain: 3 Months Follow-up
Effectiveness of Stromal Vascular Fraction (SVF) and Platelet -Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Study Protocol for a Phase III, Prospective, Randomized, Controlled Multi-center Study : (SPOST Study)
The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease
Facilitators and Barriers to Implementing Pain Neuroscience Education Programmes for the Treatment of Patients With Chronic Pain in Primary Care Physiotherapy Units: the Physiotherapist's Perspective
Comparison of Electrical Dry Needling and Therapeutic Exercise Versus Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial
Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population
Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial
Validation of a Clinical Prediction Rule to Identify Patients With Neck Pain Likely to Benefit From Cervical Spinal Manipulation: A Randomized Clinical Trial
Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis
Efficacy of Focal Vibrational Therapy in Reducing Post-stroke Shoulder Pain: a Double-blind, Randomized Controlled Trial
Comparative Efficacy of a Supervised Pulmonary Rehabilitation Program Performed 3 Days/Week Versus 1 Day/Week in Patients With Chronic Obstructive Pulmonary Disease (COPD): a Randomized Clinical Trial
Video-based First-contact Consultation With a Physiotherapist in Primary Care for Patients With Musculoskeletal Symptoms
Who cites it
1,265 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Effectiveness of Movement Representation Techniques in Chronic Non-Specific Spinal Pain: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Efficacy of high-intensity laser therapy for patellofemoral pain: a systematic review and meta-analysis.Chiropractic & manual therapies · 2026Pooled it
- The effectiveness of telerehabilitation in upper limb musculoskeletal disorders: a systematic review.BMC musculoskeletal disorders · 2026Pooled it
- Artificial intelligence software to help detect fractures on X-rays in urgent care: An Early Value Assessment.Health technology assessment (Winchester, England) · 2026Pooled it
- The adoption of innovative technologies in Physical and Rehabilitation Medicine: state of the art and unmet needs.European journal of physical and rehabilitation medicine · 2026Pooled it
- Disability and dignity: a qualitative systematic review of WASH-related barriers, facilitators and interventions for adults with musculoskeletal disabilities.Frontiers in public health · 2026Pooled it
- Artificial intelligence for prediction of clinical response and therapeutic value in interventional pain management: a scoping review.Frontiers in digital health · 2026Pooled it
- mHealth applications to enhance physical therapy outcomes among adults with chronic non-cancer pain: a scoping review.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- Virtual reality in neurorehabilitation for musculoskeletal disorders: a bibliometric analysis from 2010 to 2025.Frontiers in neurology · 2026Pooled it
- Prevention of sickness absence through early identification and rehabilitation of at-risk patients with musculoskeletal disorders (PREVSAM): a cost-effectiveness analysis comparing team-based rehabilitation in primary care vs treatment as usual.BMC health services research · 2026Trial
- Immediate clinical and neuromechanical effects of cervical spine manipulation compared to cervical spine mobilization among individuals with chronic neck pain: a randomized mechanistic cross-over trial.Chiropractic & manual therapies · 2026Trial
- TRAK MSK: a randomised external feasibility trial and process evaluation of a digital physiotherapy supported self-management programme for people with musculoskeletal pain.BMC musculoskeletal disorders · 2026Trial
- Clinical efficacy of peloidotherapy on pain, sleep quality, and central sensitization-related symptoms in chronic low back pain: a comparative analysis.International journal of biometeorology · 2026Trial
- Long-term health- and cost evaluation of two work-oriented rehabilitation models for women on long-term work disability due to common mental disorders or chronic pain - a randomized controlled trial.BMC public health · 2026Trial
- The effect of exercıse program on exercıse perceptıon and fear of movement ın low back paın.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Trial
- Verbal framing, rather than measured cognitive-affective variables, is associated with short-term outcomes after spinal manipulation: a secondary analysis of a randomized controlled trial.Pain management · 2026Trial
- Added Technology for Weight Management in Cardiac Rehabilitation: Biopsychosocial Factors and Rehabilitees' Talk in a Mixed Method Study.Journal of medical Internet research · 2026Trial
- Treatment trajectories among patients with musculoskeletal disorders in Norway - a register-based cohort study over 2 years.Scandinavian journal of primary health care · 2026Article
- Associations between osteoarthritis and comorbidities before and after diagnosis across four European primary care databases: a multinational case-control and cohort study.The Lancet regional health. Europe · 2026Article
- Durable Outcomes and Intervention Avoidance in Low Back Pain Up to 5 Years After Percutaneous 60-Day Peripheral Nerve Stimulation.Pain and therapy · 2026Article
1,205 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundRehabilitation has often been seen as a disability-specific service needed by only few of the population. Despite its individual and societal benefits, rehabilitation has not been prioritised in countries and is under-resourced. We present global, regional, and country data for the number of people who would benefit from rehabilitation at least once during the course of their disabling illness or injury.
methodsTo estimate the need for rehabilitation, data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were used to calculate the prevalence and years of life lived with disability (YLDs) of 25 diseases, impairments, or bespoke aggregations of sequelae that were selected as amenable to rehabilitation. All analyses were done at the country level and then aggregated to seven regions: World Bank high-income countries and the six WHO regions (ie, Africa, the Americas, Southeast Asia, Europe, Eastern Mediterranean, and Western Pacific).
findingsGlobally, in 2019, 2·41 billion (95% uncertainty interval 2·34-2·50) individuals had conditions that would benefit from rehabilitation, contributing to 310 million [235-392] YLDs. This number had increased by 63% from 1990 to 2019. Regionally, the Western Pacific had the highest need of rehabilitation services (610 million people [588-636] and 83 million YLDs [62-106]). The disease area that contributed most to prevalence was musculoskeletal disorders (1·71 billion people [1·68-1·80]), with low back pain being the most prevalent condition in 134 of the 204 countries analysed.
interpretationTo our knowledge, this is the first study to produce a global estimate of the need for rehabilitation services and to show that at least one in every three people in the world needs rehabilitation at some point in the course of their illness or injury. This number counters the common view of rehabilitation as a service required by only few people. We argue that rehabilitation needs to be brought close to communities as an integral part of primary health care to reach more people in need.
fundingBill & Melinda Gates Foundation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.