Evidence map›Paper›PMID 33275908›Full record

ArticleLancet (London, England)2021

Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019.

Alarcos Cieza, Kate Causey, Kaloyan Kamenov, Sarah Wulf Hanson, Somnath Chatterji, Theo Vos

Erratum issued 13 registry-linked trialsAbstract read
In one paragraph

Article in Lancet (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 13 registered trials, which are not on this map. Cited by 1,265 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,265citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05229393 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effectiveness of Manual Therapy to the Cervical Spine and Diaphragm,Combined With Breathing Reeducation Exercises, in Patients With Non-specific Chronic Neck Pain: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of West AtticaRan2022 to 2023Enrolled90ConditionsChronic Neck PainArmsCervical plus Diaphragmatic Manual Therapy plus Breathing Reeducation Exercises, Cervical Manual Therapy plus sham Diaphragmatic Manual Therapy, Conventional Physiotherapy Program
NCT05402514 completednot on this map

Digitally Delivered Exercise and Education Treatment for Shoulder Pain: 3 Months Follow-up

TypeobservationalSponsorJoint AcademyRan2021 to 2022Enrolled682ConditionsShoulder Pain, Subacromial Pain SyndromeArmsDigitally delivered exercise and education treatment Joint Academy
NCT05660824 phase4not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of Stromal Vascular Fraction (SVF) and Platelet -Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Study Protocol for a Phase III, Prospective, Randomized, Controlled Multi-center Study : (SPOST Study)

TypeinterventionalSponsorAdrien SchwitzguebelRan2025 to 2027Enrolled108ConditionsOsteoarthritisArmsStromal Vascular Fraction infiltration, Plattelet Rich Plasma infiltration
NCT05779137 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease

TypeinterventionalSponsorRadboud University Medical CenterRan2023 to 2026Enrolled174ConditionsParkinson's DiseaseArmsMBCT
NCT05860816 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Facilitators and Barriers to Implementing Pain Neuroscience Education Programmes for the Treatment of Patients With Chronic Pain in Primary Care Physiotherapy Units: the Physiotherapist's Perspective

TypeobservationalSponsorCastilla-León Health ServiceRan2023 to 2025Enrolled123ConditionsChronic Primary Pain, Musculoskeletal Pain, FibromyalgiaArmsSurvey
NCT06522893 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Electrical Dry Needling and Therapeutic Exercise Versus Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AlmeriaRan2025 to 2026Enrolled90ConditionsNeck Pain, Chronic PainArmsElectrical Dry Needling and Therapeutic exercise, Therapeutic exercise
NCT06538974 narecruitingnot on this mapstarted 2023, after this paper: background citation

Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population

TypeinterventionalSponsorWandercraftRan2023 to 2027Enrolled100ConditionsMotor Disorders, Gait Disorders, Neurologic, Neurodegenerative Diseases, Spinal Cord InjuriesArmsHands-free exoskeleton
NCT06695949 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AlmeriaRan2025 to 2025Enrolled100ConditionsNeck Pain, Chronic PainArmsPercutaneous neuromodulation., Therapeutic Exercise.
NCT06906107 narecruitingnot on this mapstarted 2025, after this paper: background citation

Validation of a Clinical Prediction Rule to Identify Patients With Neck Pain Likely to Benefit From Cervical Spinal Manipulation: A Randomized Clinical Trial

TypeinterventionalSponsorBaylor UniversityRan2025 to 2026Enrolled160ConditionsNeck Pain Musculoskeletal, Neck Pain Treatment, CervicalgiaArmsCervical Manipulation, Exercise, Mobilization
NCT07482527 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis

TypeinterventionalSponsorCairo UniversityRan2026 to 2026Enrolled60ConditionsIndividuals With Lumbar SpondylosisArmsGroup A : Core stabilization exercises (control group), Group B: Thoracic Mobility Exercises (1st experimental group only), Group C: Hip Mobility Exercises (2nd experimental group only)
NCT07513753 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of Focal Vibrational Therapy in Reducing Post-stroke Shoulder Pain: a Double-blind, Randomized Controlled Trial

TypeinterventionalSponsorUniversity of FoggiaRan2026 to 2026Enrolled60ConditionsStroke, Hemiplegic Shoulder Pain, Chronic Stroke SurvivorsArmsMultimodal Focal Vibration Therapy (FVT), Standard Rehabilitation Program
NCT07575841 nanot yet recruitingnot on this mapstarted 2027, after this paper: background citation

Comparative Efficacy of a Supervised Pulmonary Rehabilitation Program Performed 3 Days/Week Versus 1 Day/Week in Patients With Chronic Obstructive Pulmonary Disease (COPD): a Randomized Clinical Trial

TypeinterventionalSponsorHospital Universitario Fundación AlcorcónRan2027 to 2028Enrolled158ConditionsCOPD, COPD (Chronic Obstructive Pulmonary Disease)ArmsPulmonary Rehabilitation
NCT07788651 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Video-based First-contact Consultation With a Physiotherapist in Primary Care for Patients With Musculoskeletal Symptoms

TypeinterventionalSponsorVastra Gotaland RegionRan2026 to 2030Enrolled208ConditionsMusculoskeletal DiseasesArmsVideo-based first-contact physiotherapy consultation, In-person first-contact physiotherapy consultation
3 · Its place in the literature

Who cites it

1,265 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. The effect of exercıse program on exercıse perceptıon and fear of movement ın low back paın.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Trial
  16. Trial
  17. Trial
  18. Article
  19. Article
  20. Article

1,205 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alarcos CiezaSensory Functions, Disability and Rehabilitation Unit, Department for Noncommunicable Diseases, World Health Organization, Geneva, Switzerland. Electronic address: ciezaa@who.int.
Kate CauseyInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Kaloyan KamenovSensory Functions, Disability and Rehabilitation Unit, Department for Noncommunicable Diseases, World Health Organization, Geneva, Switzerland.
Sarah Wulf HansonInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Somnath ChatterjiData and Analytics Department, World Health Organization, Geneva, Switzerland.
Theo VosInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundRehabilitation has often been seen as a disability-specific service needed by only few of the population. Despite its individual and societal benefits, rehabilitation has not been prioritised in countries and is under-resourced. We present global, regional, and country data for the number of people who would benefit from rehabilitation at least once during the course of their disabling illness or injury.

methodsTo estimate the need for rehabilitation, data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were used to calculate the prevalence and years of life lived with disability (YLDs) of 25 diseases, impairments, or bespoke aggregations of sequelae that were selected as amenable to rehabilitation. All analyses were done at the country level and then aggregated to seven regions: World Bank high-income countries and the six WHO regions (ie, Africa, the Americas, Southeast Asia, Europe, Eastern Mediterranean, and Western Pacific).

findingsGlobally, in 2019, 2·41 billion (95% uncertainty interval 2·34-2·50) individuals had conditions that would benefit from rehabilitation, contributing to 310 million [235-392] YLDs. This number had increased by 63% from 1990 to 2019. Regionally, the Western Pacific had the highest need of rehabilitation services (610 million people [588-636] and 83 million YLDs [62-106]). The disease area that contributed most to prevalence was musculoskeletal disorders (1·71 billion people [1·68-1·80]), with low back pain being the most prevalent condition in 134 of the 204 countries analysed.

interpretationTo our knowledge, this is the first study to produce a global estimate of the need for rehabilitation services and to show that at least one in every three people in the world needs rehabilitation at some point in the course of their illness or injury. This number counters the common view of rehabilitation as a service required by only few people. We argue that rehabilitation needs to be brought close to communities as an integral part of primary health care to reach more people in need.

fundingBill & Melinda Gates Foundation.

Indexed as

Needs AssessmentAdolescentAdultAgedAged, 80 and overAge DistributionFemaleGlobal Burden of DiseaseGlobal HealthHumansMaleMiddle AgedMusculoskeletal DiseasesNervous System DiseasesPersons with DisabilitiesPrevalence

Identifiers

PMID33275908
PMCPMC7811204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

and 7 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.