Evidence map›Paper›PMID 33275519›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure.

Adelaeda Barrera, Humberto Morales-Loredo, Joshua M Garcia, Gisel Fregoso, Carolyn E Pace, Perenkita J Mendiola, Jay S Naik, Laura V Gonzalez Bosc, Nancy L Kanagy

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Taking to "heart" the proposed legislation for permanent daylight saving time.American journal of physiology. Heart and circulatory physiology · 2022
    Article
  6. Sympathetic neural responses to sleep disorders and insufficiencies.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adelaeda BarreraVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Humberto Morales-LoredoVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Joshua M GarciaVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Gisel FregosoVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Carolyn E PaceVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Perenkita J MendiolaVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Jay S NaikVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-5725-4664
Laura V Gonzalez BoscVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Nancy L KanagyVascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-9028-4021
University of New Mexico · US

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
MINORITY INSTITUTIONAL RESEARCH TRAINING PROGRAM (T32)T32HL007736 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 1993 to 2025
$6.5M
Hydrogen sulfide regulation of vascular tone and blood pressureR01HL123301 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI KANAGY, NANCY L · 2015 to 2018
$1.5M
HHS | NIH | National Cancer Institute (NCI) 2P30CA118100HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) HL007736HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) HL123301NCI NIH HHS P30 CA118100NHLBI NIH HHS R01 HL123301NHLBI NIH HHS T32 HL007736
6 · The paper itself

Abstract

In sleep apnea, airway obstruction causes intermittent hypoxia (IH). In animal studies, IH-dependent hypertension is associated with loss of vasodilator hydrogen sulfide (H

Indexed as

Blood CirculationBlood PressureAlkynesAnimalsAntihypertensive AgentsCarotid BodyCystathionine gamma-LyaseEnzyme InhibitorsGasotransmittersGlycineHexamethoniumHydrogen SulfideMaleMesenteric ArteriesRatsRats, Sprague-DawleyAlkynesAntihypertensive AgentsCystathionine gamma-LyaseEnzyme InhibitorsGasotransmittersGlycineHexamethoniumHydrogen Sulfidepropargylglycineblood flowcarotid bodycystathionine γ-lyaseintermittent hypoxiamesenteric arteries

Identifiers

PMID33275519
PMCPMC8082798
OpenAlexW3108227567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.