Evidence map›Paper›PMID 33275070›Full record

Trial reportMicrobial drug resistance (Larchmont, N.Y.)2020

High Prevalence of Fecal Carriage of Extended Spectrum β-Lactamase-Producing Enterobacteriaceae Among Newly HIV-Diagnosed Adults in a Community Setting in Tanzania.

Joel Manyahi, Sabrina John Moyo, Marit Gjerde Tellevik, Nina Langeland, Bjørn Blomberg

Erratum issuedOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Microbial drug resistance (Larchmont, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  8. Multidrug-Resistant Bacteria in Immunocompromised Patients.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joel ManyahiDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Sabrina John MoyoDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Marit Gjerde TellevikNational Advisory Unit on Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway.
Nina LangelandDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Bjørn BlombergDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Haukeland University Hospital · NOMuhimbili University of Health and Allied Sciences · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colonization in HIV-infected populations with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is particularly worrisome in low-income settings. This study describes the prevalence of ESBL-PE carriage and associated risk factors among newly HIV-diagnosed adults in a community setting in Tanzania. A total of 595 newly diagnosed HIV adults with a median age of 35 years with interquartile range (IQR) 29-42 years and a median CD4 count of 492 cells/μL (IQR 390-666 cells/μL) were recruited. Among these, 194/595 (32.6%, 95% confidence interval [CI] 28.9-36.6) were ESBL-PE carriers. Participants with low CD4 count (<350 cells/μL) had significantly higher prevalence of ESBL-PE carriage compared with those with CD4 count ≥350 cells/μL (26/58, 44.8%, vs. 168/537, 31.3%,

Indexed as

AdultAge FactorsAnti-Bacterial Agentsbeta-Lactam ResistanceCarrier StateCD4 Lymphocyte CountDouble-Blind MethodEnterobacteriaceaeEnterobacteriaceae InfectionsFecesFemaleGenes, BacterialHIV InfectionsHumansMaleMiddle AgedAnti-Bacterial AgentscommunityESBLHIVTanzania

Identifiers

PMID33275070
PMCPMC7757532
OpenAlexW3106729691

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.