Evidence map›Paper›PMID 33274773›Full record

ReviewPsychophysiology2021

Emotion context insensitivity in depression: Toward an integrated and contextualized approach.

Lauren M Bylsma

Abstract readReview
In one paragraph

Review in Psychophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Evidence Base Update for Questionnaires of Emotion Regulation and Reactivity for Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Emotional Blunting and Time Estimation in Depression.Biological psychiatry global open science · 2026
    Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lauren M BylsmaDepartments of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-3828-1760

Funding

CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
Yearly Workshop in the Event-Related Potential TechniqueR25MH080794 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Emily S. Kappenman, STEVEN J LUCK · 2007 to 2026
$2.6M
Emotion Regulation in Distress Disorders: Elucidating the Role of Cognitive Processes and Person-Situation Fit in the Laboratory and Daily LifeR01MH118218 · NIMH · UNIVERSITY OF WESTERN AUSTRALIA · PI GAINEY, KRISTIN · 2019 to 2023
$2.2M
Neurobehavioral Predictors of Emotional Deficits in Youth at Risk for DepressionK01MH104325 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BYLSMA, LAUREN M · 2014 to 2017
$629k
Vagal fluctuation as a predictor of current and future depressionR21MH077669 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI ROTTENBERG, JONATHAN ADAM · 2008 to 2009
$363k
NIMH NIH HHS K01 MH104325NIMH NIH HHS L30 MH101750NIMH NIH HHS MH018951NIMH NIH HHS MH077669NIMH NIH HHS MH080794NIMH NIH HHS MH101750NIMH NIH HHS MH104325NIMH NIH HHS MH118218NIMH NIH HHS R01 MH118218NIMH NIH HHS R21 MH077669NIMH NIH HHS R25 MH080794NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

Major depressive disorder (MDD) is characterized by pervasive mood disturbance as well as deficits in emotional processing, reactivity, and regulation. There is accumulating evidence that MDD is characterized by emotional patterns consistent with environmental disengagement, as reflected in attenuated positive and negative emotional reactivity, consistent with Emotion Context Insensitivity (ECI) theory. However, MDD individuals vary considerably in the extent to which they exhibit specific alterations in patterns of emotional responding. Emotions are complex, multicomponent processes that invoke responses across multiple functional domains and levels of analysis, including subjective experience, behavior, autonomic regulation, cognition, and neural processing. In this article, I review the current state of the literature on emotional responding and MDD from the lens of ECI. I focus on the importance of assessing emotional indices from multiple levels of analysis across development and contexts. I also discuss methodological and measurement issues that may contribute to inconsistent findings. In particular, I emphasize how psychophysiological measures can help elucidate emotional processes that underlie the pathophysiology of MDD as part of an integrated and contextualized approach.

Indexed as

RewardAffectAffective SymptomsAutonomic Nervous SystemCryingEvoked PotentialsHumansMajor Depressive DisorderRespiratory Sinus ArrhythmiaStress, PsychologicalcontextdepressiondevelopmentECIemotionflexibilitypsychophysiology

Identifiers

PMID33274773
PMCPMC8097691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.