ArticleeLife2020
Activation of the archaeal ion channel MthK is exquisitely regulated by temperature.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Beyond Small Molecules: Orchestrating Cell Fate with Engineered Water-Soluble Membrane Proteins.Biomolecules · 2026Article
- Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs.bioRxiv : the preprint server for biology · 2024Article
- Vertebrate behavioral thermoregulation: knowledge and future directions.Neurophotonics · 2024Review
- Forces and energetics of the canonical tetrameric cation channel gating.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Post-injury pain and behaviour: a control theory perspective.Nature reviews. Neuroscience · 2023Review
- Ion Conduction Mechanisms in Potassium Channels Revealed by Permeation Cycles.Journal of chemical theory and computation · 2023Article
- Ion channel thermodynamics studied with temperature jumps measured at the cell membrane.Biophysical journal · 2023Article
- Acylated and alkylated benzo(crown-ethers) form ion-dependent ion channels in biological membranes.Biophysical journal · 2022Article
- Bio-Mimicking, Electrical Excitability Phenomena Associated With Synthetic Macromolecular Systems: A Brief Review With Connections to the Cytoskeleton and Membraneless Organelles.Frontiers in molecular neuroscience · 2022Review
- Preparation of GiantBio-protocol · 2021Article
- Towards the Idea of Molecular Brains.International journal of molecular sciences · 2021Review
- Blowing Hot and Cold: Body Temperature and the Microbiome.mSystems · 2021Article
- Mapping Electromechanical Coupling Pathways in Voltage-Gated Ion Channels: Challenges and the Way Forward.Journal of molecular biology · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Physiological response to thermal stimuli in mammals is mediated by a structurally diverse class of ion channels, many of which exhibit polymodal behavior. To probe the diversity of biophysical mechanisms of temperature-sensitivity, we characterized the temperature-dependent activation of MthK, a two transmembrane calcium-activated potassium channel from thermophilic archaebacteria. Our functional complementation studies show that these channels are more efficient at rescuing K
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.