ArticleeLife2020
A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Identification and Expression Profiling of Scorpion Ionotropic Receptors and Gustatory Receptors Based on the Transcriptomic Analysis.Integrative zoology · 2026Article
- Genomic Identification and Comparative Characterization of Chemosensory Genes in Two Walnut Pests.Biology · 2026Article
- Early hexapod genomes reveal the deep origin of insect gustatory and odorant receptors.Nature communications · 2026Article
- Article
- A structural perspective on insect gustatory receptors.Chemical senses · 2025Review
- Accelerating Ligand Discovery for Insect Odorant Receptors.International journal of biological sciences · 2025Article
- TBM preferred to AlphaFold 3 for functional models of insect odorant receptors.Computational and structural biotechnology journal · 2025Article
- cGMP-dependent pathway and a GPCR kinase are required for photoresponse in the nematode Pristionchus pacificus.PLoS genetics · 2024Article
- Evolution of Sensory Receptors.Annual review of cell and developmental biology · 2024Review
- Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids.Nature communications · 2024Article
- Structural screens identify candidate human homologs of insect chemoreceptors and crypticeLife · 2023Article
- Rational engineering approaches for establishing insect olfaction reporters in yeast.Biotechnology notes (Amsterdam, Netherlands) · 2023Article
- Review
- Sweet sensors support stressed cell survival.PLoS biology · 2022Article
- Reverse chemical ecology in a moth: machine learning on odorant receptors identifies new behaviorally active agonists.Cellular and molecular life sciences : CMLS · 2021Article
- A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor.eLife · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The insect chemosensory repertoires of Odorant Receptors (ORs) and Gustatory Receptors (GRs) together represent one of the largest families of ligand-gated ion channels. Previous analyses have identified homologous 'Gustatory Receptor-Like' (GRL) proteins across Animalia, but the evolutionary origin of this novel class of ion channels is unknown. We describe a survey of unicellular eukaryotic genomes for GRLs, identifying several candidates in fungi, protists and algae that contain many structural features characteristic of animal GRLs. The existence of these proteins in unicellular eukaryotes, together with
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.