Evidence map›Paper›PMID 33274667›Full record

Trial reportGut microbes2020

Personalized B cell response to the

Jette Bornholdt, Christa Broholm, Yun Chen, Alfredo Rago, Stine Sloth, Jakob Hendel, Cathrine Melsæther, Christina V Müller, Maria Juul Nielsen, Jesper Strickertsson and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Molecular Mechanisms ofMicroorganisms · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Frontiers in immunology · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jette BornholdtBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Christa BroholmBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Yun ChenBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Alfredo RagoBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Stine SlothGastro Unit, Herlev Hospital, University of Copenhagen , Herlev, Denmark.
Jakob HendelGastro Unit, Herlev Hospital, University of Copenhagen , Herlev, Denmark.
Cathrine MelsætherHuman Health Discovery , Hørsholm, Denmark.
Christina V MüllerBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Maria Juul NielsenBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Jesper StrickertssonBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Lars EngelholmBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Kristoffer Vitting-SeerupBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Kim B JensenBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.
Adam BakerHuman Health Discovery , Hørsholm, Denmark.
Albin SandelinBiotech Research and Innovation Centre, University of Copenhagen , Copenhagen N, Denmark.ORCID 0000-0002-7109-7378
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific effects of administering live probiotics in the human gut are not well characterized. To this end, we investigated the immediate effect of

Indexed as

AdultB-LymphocytesCross-Over StudiesDNA, BacterialFemaleGastrointestinal MicrobiomeGene ExpressionGene Expression RegulationHealthy VolunteersHumansJejunumLacticaseibacillus rhamnosusLymphocyte ActivationMaleProbioticsSex FactorsDNA, BacterialB cell activationhuman transcriptomicsimmediate in vivo effectLactobacillus rhamnosus GGprobiotics

Identifiers

PMID33274667
PMCPMC7722709
OpenAlexW3106906614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.