Evidence map›Paper›PMID 33274521›Full record

ArticleClinical transplantation2021

Donor management using a specialized donor care facility is associated with higher organ utilization from drug overdose donors.

Christian Corbin Frye, Jason M Gauthier, Amit Bery, William D Gerull, Deniz B Morkan, Jingxia Liu, M Shea Harrison, Yuriko Terada, Judith E Van Zanden, Gary F Marklin and 11 more

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Same-teams versus different-teams for long distance lung procurement: A cost analysis.The Journal of thoracic and cardiovascular surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Christian Corbin FryeDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-4323-0696
Jason M GauthierDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0003-3326-8727
Amit BeryDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
William D GerullDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Deniz B MorkanDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Jingxia LiuDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
M Shea HarrisonDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Yuriko TeradaDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Judith E Van ZandenDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0003-0095-2098
Gary F MarklinMid-America Transplant, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0003-2920-4835
Michael K PasqueDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Ruben G NavaDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Bryan F MeyersDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Alexander G PattersonDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Benjamin D KozowerDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Ramsey HachemDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-0708-1937
Derek ByersDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Chad WittDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Hrishikesh KulkarniDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Daniel KreiselDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-7711-8651
Varun PuriDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Washington University in St. Louis · US

Funding

PRINCIPLES IN PULMONARY RESEARCHT32HL007317 · NHLBI · WASHINGTON UNIVERSITY · PI Steven Brody, Michael J Holtzman · 1985 to 2026
$16.1M
Optimizing Donor Management in Lung TransplantationR01HL146856 · NHLBI · WASHINGTON UNIVERSITY · PI Ana Baumann Walker, Matthew Galen Hartwig · 2020 to 2026
$2.7M
NHLBI NIH HHS R01 HL146856NHLBI NIH HHS T32 HL007317
6 · The paper itself

Abstract

Drug overdoses have tripled in the United States over the last two decades. With the increasing demand for donor organs, one potential consequence of the opioid epidemic may be an increase in suitable donor organs. Unfortunately, organs from donors dying of drug overdose have poorer utilization rates than other groups of brain-dead donors, largely due to physician and recipient concerns about viral disease transmission. During the study period of 2011 to 2016, drug overdose donors (DODs) account for an increasingly greater proportion of the national donor pool. We show that a novel model of donor care, known as specialized donor care facility (SDCF), is associated with an increase in organ utilization from DODs compared to the conventional model of hospital-based donor care. This is likely related to the close relationship of the SDCF with the transplant centers, leading to improved communication and highly efficient donor care.

Indexed as

Drug OverdoseTissue and Organ ProcurementAnalgesics, OpioidBrain DeathHumansTissue DonorsUnited StatesAnalgesics, Opioiddonors and donationorgan allocationScientific Registry for Transplant Recipients

Identifiers

PMID33274521
PMCPMC8248520
OpenAlexW3107651203

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.