ReviewClinical rheumatology2021
Synovial biopsies in clinical practice and research: current developments and perspectives.
Review in Clinical rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Ultrasound-Guided Synovial Biopsy in Chronic Knee Monoarthritis: A Case Series Highlighting Its Diagnostic Value.Cureus · 2026Article
- Decoding Temporomandibular Disorders: Identifying Stage-Specific and Functional Patterns in the Articular Disc.Stem cell reviews and reports · 2026Review
- Ultrasound-guided core needle joint biopsies in children: pathological findings, diagnostic performance, and clinical relevance.Pediatric radiology · 2026Article
- The value of contrast-enhanced ultrasound in synovial pathotypes of rheumatoid arthritis: an exploratory study.European radiology · 2026Article
- Biopsy-Driven Synovial Pathophenotyping in RA: A New Approach to Personalized Treatment.Journal of personalized medicine · 2025Review
- Artificial intelligence in rheumatology: A transformative perspective.Journal of translational internal medicine · 2025Article
- Ultrasound-Guided Synovial Biopsy in Undifferentiated Monoarthritis: A Case Series From Bangladesh.Cureus · 2025Article
- Article
- Septic Arthritis of the Knee in Children.Cureus · 2023Review
- Image-guided synovial biopsy with a focus on neoplastic lesions.Skeletal radiology · 2023Review
- In-Office Needle Arthroscopic Synovial Biopsy Is an Effective Diagnostic Tool in Patients With Inflammatory Arthritis.Arthroscopy, sports medicine, and rehabilitation · 2022Article
- Inside the Joint of Inflammatory Arthritis Patients: Handling and Processing of Synovial Tissue Biopsies for High Throughput Analysis.Frontiers in medicine · 2022Review
- Current Practice of Imaging-Guided Interventional Procedures in Rheumatic and Musculoskeletal Diseases: Results of a Multinational Multidisciplinary Survey.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synovial biopsy techniques have developed and widely expanded over the past few years, in particular due to the development of ultrasound-guided procedures. This article reviews the different techniques, clinical applications, and the latest advances in translational research as well as current challenges and perspectives. The first part focuses on different techniques available for biopsy, along with their feasibility, success rate, tolerance, and training requirements. In the second part, clinical applications are described. Data on diagnostic performances are reported, especially regarding septic arthritis. Translational research applications are described and explained in the final part, from the early histological studies and the first description of pathotype to more recent technologies involving -omics. Latest developments involving single-cell RNA sequence analysis have allowed the discovery of new cell subpopulations with remarkable roles in RA pathophysiology. These studies pave the ground for the discovery of new therapeutic targets and the implementation of personalized therapy in RA. Key Point •This review provides an overview of synovial biopsy techinques and applications especially in clinical and translational research.
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