ArticleJournal of travel medicine2021
Curbing the COVID-19 pandemic with facility-based isolation of mild cases: a mathematical modeling study.
Article in Journal of travel medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Effect of Isolation Measures on Nosocomial Infection Rates in Nursing Practice during COVID-19: A Meta-Analysis.Iranian journal of public health · 2025Review
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- Preferences regarding COVID-19 vaccination among 12,000 adults in China: A cross-sectional discrete choice experiment.PLOS global public health · 2024Article
- Comparing COVID-19 Case Prediction Between ARIMA Model and Compartment Model - China, December 2019-April 2020.China CDC weekly · 2022Article
- Attitudes Toward the Global Allocation of Chinese COVID-19 Vaccines: Cross-sectional Online Survey of Adults Living in China.JMIR public health and surveillance · 2022Article
- Factors Predicting Progression to Severe COVID-19: A Competing Risk Survival Analysis of 1753 Patients in Community Isolation in Wuhan, China.Engineering (Beijing, China) · 2022Article
- Prevalence of depression in China during the early stage of the COVID-19 pandemic: a cross-sectional study in an online survey sample.BMJ open · 2022Article
- Risk factors associated with hospital transfer among mild or asymptomatic COVID-19 patients in isolation facilities in Tokyo: a case-control study.IJID regions · 2022Article
- Term Neonatal Complications During the Second Localized COVID-19 Lockdown and Prolonged Premature Rupture of Membranes at Home Among Nulliparas With Reference Interval for Maternal C-Reactive Protein: A Retrospective Cohort Study.Frontiers in pediatrics · 2022Article
- Medical implementation practice and its medical performance evaluation of a giant makeshift hospital during the COVID-19 pandemic: An innovative model response to a public health emergency in Shanghai, China.Frontiers in public health · 2022Article
- Preferences and patterns of response to public health advice during the COVID-19 pandemic.Scientific reports · 2021Article
- Macro-level efficiency of health expenditure: Estimates for 15 major economies.Social science & medicine (1982) · 2021Article
- Facilities for Centralized Isolation and Quarantine for the Observation and Treatment of Patients with COVID-19.Engineering (Beijing, China) · 2021Article
- The East-West Divide in Response to COVID-19.Engineering (Beijing, China) · 2021Article
- Knowledge About COVID-19 Among Adults in China: Cross-sectional Online Survey.Journal of medical Internet research · 2021Article
- Climate and the spread of COVID-19.Scientific reports · 2021Article
- Practice in Information Technology Support for Fangcang Shelter Hospital during COVID-19 Epidemic in Wuhan, China.Journal of medical systems · 2021Article
- One Year in: Lessons from China's Fight Against COVID-19.China CDC weekly · 2021Article
- Singapore's Pandemic Preparedness: An Overview of the First Wave of COVID-19.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
Abstract
backgroundIn many countries, patients with mild coronavirus disease 2019 (COVID-19) are told to self-isolate at home, but imperfect compliance and shared living space with uninfected people limit the effectiveness of home-based isolation. We examine the impact of facility-based isolation compared to self-isolation at home on the continuing epidemic in the USA.
methodsWe developed a compartment model to simulate the dynamic transmission of COVID-19 and calibrated it to key epidemic measures in the USA from March to September 2020. We simulated facility-based isolation strategies with various capacities and starting times under different diagnosis rates. Our primary model outcomes are new infections and deaths over 2 months from October 2020 onwards. In addition to national-level estimations, we explored the effects of facility-based isolation under different epidemic burdens in major US Census Regions. We performed sensitivity analyses by varying key model assumptions and parameters.
resultsWe find that facility-based isolation with moderate capacity of 5 beds per 10 000 total population could avert 4.17 (95% credible interval 1.65-7.11) million new infections and 16 000 (8000-23 000) deaths in 2 months compared with home-based isolation. These results are equivalent to relative reductions of 57% (44-61%) in new infections and 37% (27-40%) in deaths. Facility-based isolation with high capacity of 10 beds per 10 000 population could achieve reductions of 76% (62-84%) in new infections and 52% (37-64%) in deaths when supported by expanded testing with an additional 20% daily diagnosis rate. Delays in implementation would substantially reduce the impact of facility-based isolation. The effective capacity and the impact of facility-based isolation varied by epidemic stage across regions.
conclusionTimely facility-based isolation for mild COVID-19 cases could substantially reduce the number of new infections and effectively curb the continuing epidemic in the USA. Local epidemic burdens should determine the scale of facility-based isolation strategies.
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