Evidence map›Paper›PMID 33274246›Full record

ArticleJournal of immunology research2020

Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An

Hamza Arshad Dar, Yasir Waheed, Muzammil Hasan Najmi, Saba Ismail, Helal F Hetta, Amjad Ali, Khalid Muhammad

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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  11. A novel vaccine based on SARS-CoV-2 CD4Scientific reports · 2022
    Article
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  17. A contemporary review on the important role ofInformatics in medicine unlocked · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Hamza Arshad DarFoundation University Medical College, Foundation University Islamabad, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-0667-5653
Yasir WaheedFoundation University Medical College, Foundation University Islamabad, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-5789-4215
Muzammil Hasan NajmiFoundation University Medical College, Foundation University Islamabad, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-6114-5540
Saba IsmailFoundation University Medical College, Foundation University Islamabad, Islamabad 44000, Pakistan.
Helal F HettaDepartment of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0595, USA.ORCID https://orcid.org/0000-0001-8541-7304
Amjad AliAtta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-0486-4661
Khalid MuhammadDepartment of Biology, College of Science, United Arab Emirates University, Al Ain 15551, UAE.ORCID https://orcid.org/0000-0001-6488-1722
Foundation University Islamabad · PKNational University of Sciences and Technology · PKSabin Vaccine Institute · USUnited Arab Emirates University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global health crisis caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, has resulted in a negative impact on human health and on social and economic activities worldwide. Researchers around the globe need to design and develop successful therapeutics as well as vaccines against the novel COVID-19 disease. In the present study, we conducted comprehensive computer-assisted analysis on the spike glycoprotein of SARS-CoV-2 in order to design a safe and potent multiepitope vaccine.

Indexed as

Amino Acid SequenceComputational BiologyComputer SimulationCOVID-19COVID-19 VaccinesEpitopes, B-LymphocyteEpitopes, T-LymphocyteHumansHydrogen BondingImmunogenicity, VaccineMolecular Docking SimulationPandemicsSARS-CoV-2Spike Glycoprotein, CoronavirusStatic ElectricityThermodynamicsCOVID-19 VaccinesEpitopes, B-LymphocyteEpitopes, T-LymphocyteSpike Glycoprotein, CoronavirusVaccines, Subunit

Identifiers

PMID33274246
PMCPMC7678744
OpenAlexW3109645630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.