Evidence map›Paper›PMID 33274024›Full record

ArticleClinics in orthopedic surgery2020

Economic Burden of Periprosthetic Joint Infection Following Primary Total Knee Replacement in a Developing Country.

Faizan Iqbal, Bilal Shafiq, Syed Shahid Noor, Zulfiqar Ali, Nouman Memon, Naveed Memon

Abstract read
In one paragraph

Article in Clinics in orthopedic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Mid-term performance of a unicompartmental knee prosthesis.Journal of experimental orthopaedics · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Total knee arthroplasty and periprosthetic distal femoral fracture: looking beyond the osteoporosis to previous osteoporotic fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faizan IqbalDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.
Bilal ShafiqDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.
Syed Shahid NoorDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.
Zulfiqar AliDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.
Nouman MemonDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.
Naveed MemonDepartment of Orthopedic Surgery Liaquat National Hospital and Medical College, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriprosthetic joint infection is one of the devastating complications after primary total knee arthroplasty, which increases the financial burden on patients and affects their quality of life as well. The financial burden of periprosthetic joint infection after joint replacement in developed countries is well known. There is a need to evaluate the economic burden in developing countries such as Pakistan.

methodsThis is a single-center, retrospective, case-control study conducted at the Department of Orthopedic Surgery, Liaquat National Hospital Karachi. Cases of primary total knee arthroplasty performed during this study were divided into 2 groups: uneventful primary total knee arthroplasty and periprosthetic joint infection treated with 2-stage revision. To calculate the final cost, we divided the total hospital cost into the hospital stay cost and operating room cost.

resultsDuring study period, 32 patients were diagnosed with periprosthetic joint infection. The total cost of revision surgery for periprosthetic joint infection considering 2 hospitalizations was 1,780,222 ± 313,686 Pakistani rupee (PKR). The total cost of uneventful arthroplasty was 390,172 ± 51,460 PKR. We observed significant difference with respect to economic details between the 2 groups.

conclusionsManagement of periprosthetic joint infection was 4.5 times more expensive than uneventful primary total knee arthroplasty. Measures should be undertaken to reduce the prevalence of periprosthetic joint infection, thereby reducing patients' economic burden.

Indexed as

Cost of IllnessArthroplasty, Replacement, KneeCase-Control StudiesDeveloping CountriesFemaleHumansMaleMiddle AgedPostoperative ComplicationsProsthesis-Related InfectionsQuality of LifeReoperationRetrospective StudiesEconomic burdenPeriprosthetic joint infectionRevision surgeryTotal knee arthroplasty

Identifiers

PMID33274024
PMCPMC7683183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.