Evidence map›Paper›PMID 33274009›Full record

ArticleOxidative medicine and cellular longevity2020

Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice.

Siming Fu, Xu Luo, Xuan Wu, Tongyu Zhang, Linggui Gu, Yiying Wang, Meng Gao, Yuan Cheng, Zongyi Xie

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Localization of Melanocortin 1 Receptor in the Substantia Nigra.International journal of molecular sciences · 2024
    Article
  4. The Skin-Brain Axis: From UV and Pigmentation to Behaviour Modulation.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Siming FuDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Xu LuoDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Xuan WuDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Tongyu ZhangDepartment of Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Linggui GuDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Yiying WangDepartment of Human Anatomy, Chongqing Medical University, Chongqing 400016, China.
Meng GaoDepartment of Human Anatomy, Chongqing Medical University, Chongqing 400016, China.
Yuan ChengDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Zongyi XieDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.ORCID https://orcid.org/0000-0003-2991-1732
Dalian Medical University · CNChongqing Medical University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and neuronal apoptosis play crucial roles in secondary brain injury (SBI) after intracerebral hemorrhage (ICH). Recently, Nle4-D-Phe7-

Indexed as

alpha-MSHAnimalsApoptosisCerebral HemorrhageMaleMiceNeuronsNF-E2-Related Factor 2Oxidative StressPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptor, Melanocortin, Type 1Signal Transductionalpha-MSHMSH, 4-Nle-7-Phe-alpha-Nfe2l2 protein, mouseNF-E2-Related Factor 2Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptor, Melanocortin, Type 1

Identifiers

PMID33274009
PMCPMC7676969
OpenAlexW3105666127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.