Evidence map›Paper›PMID 33274005›Full record

ArticleOxidative medicine and cellular longevity2020

Chrysophanol Alleviates Metabolic Syndrome by Activating the SIRT6/AMPK Signaling Pathway in Brown Adipocytes.

Xueying Liu, Zehong Yang, Huixuan Li, Wen Luo, Wentao Duan, Junmei Zhang, Zhangzhi Zhu, Min Liu, Saimei Li, Xiaoyi Xin and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Xueying LiuThe First Clinical Medical College of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Zehong YangArtemisinin Research Center, Guangzhou University of Chinese Medicine, 12 Airport Road, Guangzhou 510405, China.
Huixuan LiScience and Technology Innovation Center, Piwei Institute, Guangzhou University of Chinese Medicine, 12 Airport Road, Guangzhou 510405, China.
Wen LuoThe First Clinical Medical College of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Wentao DuanScience and Technology Innovation Center, Piwei Institute, Guangzhou University of Chinese Medicine, 12 Airport Road, Guangzhou 510405, China.
Junmei ZhangDepartment of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Zhangzhi ZhuDepartment of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Min LiuDepartment of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Saimei LiThe First Clinical Medical College of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Xiaoyi XinDepartment of Chinese Medicine, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China.
Haoxiang WuDepartment of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.
Shaoxiang XianThe First Clinical Medical College of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.ORCID https://orcid.org/0000-0002-9266-313X
Meijing LiuBeijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, Beihang University, Beijing 100191, China.ORCID https://orcid.org/0000-0002-9785-8614
Changhui LiuSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 12 Airport Road, Guangzhou 510405, China.ORCID https://orcid.org/0000-0001-6165-4313
Chuangpeng ShenThe First Clinical Medical College of Guangzhou University of Chinese Medicine, 16 Airport Road, Guangzhou 510405, China.ORCID https://orcid.org/0000-0003-3664-5380
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chrysophanol, a primary active ingredient of

Indexed as

Adipocytes, BrownAMP-Activated Protein KinasesAnimalsAnthraquinonesMaleMetabolic SyndromeMiceMice, KnockoutSignal TransductionSirtuinsAMP-Activated Protein KinasesAnthraquinoneschrysophanic acidSirt6 protein, mouseSirtuins

Identifiers

PMID33274005
PMCPMC7683138
OpenAlexW3098391225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.