Evidence map›Paper›PMID 33273969›Full record

ArticleExperimental and therapeutic medicine2021

Role of the stromal cell derived factor-1 in the biological functions of endothelial progenitor cells and its underlying mechanisms.

Yanping Cun, Bo Diao, Zhimin Zhang, Gang Wang, Jing Yu, Lianting Ma, Zhiguo Rao

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yanping CunDepartment of Oncology, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Bo DiaoDepartment of Clinical Experiment, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Zhimin ZhangDepartment of Oncology, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Gang WangDepartment of Clinical Experiment, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Jing YuDepartment of Clinical Experiment, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Lianting MaDepartment of Neurosurgery, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Zhiguo RaoDepartment of Oncology, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
General Hospital of Central Theater CommandCentral Hospital of Wuhan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stromal cell derived factor-1 (SDF-1) is a chemokine that plays a critical role in the homing of stem and progenitor cells, including endothelial progenitor cells (EPCs). However, little research has been undertaken to evaluate the roles of SDF-1 in the biological functions of EPCs and related signaling pathways. The present study aimed to investigate the biological functions of EPCs in response to SDF-1, as well as the underlying mechanisms. The effects of SDF-1 treatment on EPC proliferation, migration and tube formation were assessed by performing MTS, Transwell and

Indexed as

Akt signaling pathwaybiological functionsendothelial progenitor cellsERK signaling pathwaystromal cell derived factor-1

Identifiers

PMID33273969
PMCPMC7706408
OpenAlexW3101380075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.