Evidence map›Paper›PMID 33273921›Full record

ArticleJournal of cancer epidemiology2020

Prognostic Worth of Epidermal Growth Factor Receptor (EGFR) in Patients with Head and Neck Tumors.

Precious Barnes, F A Yeboah, Jinling Zhu, Roland Osei Saahene, Christian Obirikorang, Michael Buenor Adinortey, Benjamin Amoani, Foster Kyei, Patrick Akakpo, Yaw Asante Awuku

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Precious BarnesDepartment of Physician Assistant Studies, College of Health and Allied Sciences School of Allied Health Sciences, University of Cape Coast, Ghana.ORCID https://orcid.org/0000-0002-9229-5605
F A YeboahDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Ghana.
Jinling ZhuDepartment of Biology, School of Medical Sciences, Jiamusi University China, China.
Roland Osei SaaheneDepartment of Microbiology and Immunology, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Christian ObirikorangDepartment of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Ghana.
Michael Buenor AdinorteyDepartment of Biochemistry, School of Biological Sciences, College of Agricultural and Natural Sciences, University of Cape Coast, Ghana.
Benjamin AmoaniDepartment of Biomedical Sciences, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Ghana.ORCID https://orcid.org/0000-0002-4086-3033
Foster KyeiDepartment of Molecular Biology and Biotechnology, School of Biological Sciences, College of Agricultural and Natural Sciences, University of Cape Coast, Ghana.
Patrick AkakpoDepartment of Pathology, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Yaw Asante AwukuDepartment of Internal Medicine, School of Medical Sciences, University of Health and Allied Sciences, Ghana.
University of Cape Coast · GHKwame Nkrumah University of Science and Technology · GHJiamusi University · CNUniversity of Health and Allied Sciences · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHead and neck tumors (HNT) are tumors that normally occur at the head and neck region of the body. Epidermal growth factor receptor (EGFR) has been found to be highly expressed in breast and other tumors; therefore, there is the need to investigate the level of EGFR expression among patients with head and neck tumors in Ghana.

methodThe level of EGFR expression was determined in head and neck tumor and control head and neck tissues with quantitative real-time PCR and immunohistochemistry analysis.

resultsThe level of EGFR expressions was high in tumor tissues than in the control tissues. There was a significant difference of

conclusionEGFR can serve as a prognostic marker in monitoring patients with HNT as well as a molecular therapeutic target.

Identifiers

PMID33273921
PMCPMC7683104
OpenAlexW3099431645

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.