ArticleBioinorganic chemistry and applications2020
Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells.
Article in Bioinorganic chemistry and applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Urinary Angiogenin as a Marker for Bladder Cancer: A Meta-Analysis.BioMed research international · 2021Pooled it
- Synthesis of Padina boergesenii-Derived Zinc Oxide Nanoparticles and their Therapeutic Potential Against Oral Squamous Cell Carcinoma: A Transcriptomic and in Vitro Evaluation.Applied biochemistry and biotechnology · 2026Article
- Smart and bioactive packaging systems from anthocyanins and zinc oxide nanoparticles for quality monitoring and shelf-life extension of Nile perch (Lates niloticus).Scientific reports · 2026Article
- Induction of Apoptosis in Colorectal Cancer Cells by Zinc Oxide Nanoparticles Extracted From Lactiplantibacillus plantarum With Gene Expression Control of Apoptosis-Related Genes.BioMed research international · 2026Article
- Quercetin-loaded zinc oxide nanoparticles encapsulated in chitosan-alginate: a synergistic approach to cancer and bacterial therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Article
- Green-synthesized zinc oxide nanoparticles using Echinops spinosus extract: A promising anticancer agent for hepatocellular carcinoma.PloS one · 2025Article
- Chronic constipation and the brain-gut-microbiome axis: the role of 5-HT signaling and Traditional Chinese Medicine in pathophysiology and treatment.Frontiers in medicine · 2025Review
- Synthesis, characterization, and photocatalytic activities of green sol-gel ZnO nanoparticles usingHeliyon · 2024Article
- Article
- Review
- Green synthesis of zinc oxide nanoparticles usingRoyal Society open science · 2022Article
- Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties.Bioengineering (Basel, Switzerland) · 2022Review
- Article
- A Comprehensive Review of the Development of Carbohydrate Macromolecules and Copper Oxide Nanocomposite Films in Food Nanopackaging.Bioinorganic chemistry and applications · 2022Review
- Anticancer and Free Radical Scavenging Competence of Zinc Oxide Nanoparticles Synthesized by Aqueous Leaf Extract ofBioinorganic chemistry and applications · 2022Article
- Antibacterial and Photocatalytic Properties of ZnO Nanoparticles Obtained from Chemical versusMolecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in the expression of microRNAs can affect cancer cells' viability and behavior and the impact on cancer treatment. In this study, the expression of miR-155-5p, miR-203a-3p, and miR-223-3p in the MCF7 cancer cell line was studied when exposed to ZnO nanoparticles synthesized through a green route. Mentioned ZnO-NPs were well characterized by UV-vis spectroscopy, DLS, XRD, FTIR, FE-SEM, EDX, zeta potential, and AFM analyses. Cellular studies were conducted using ZnO-NPs before miRNA investigations including MTT cytotoxicity test against MCF7, MDA-MB-231, and HFF cell lines. Moreover, apoptosis assays were performed using morphological analysis, fluorescent dyes, flow cytometry, and evaluation of caspase-3 and caspase-8 gene expression. Biological properties such as the antioxidant and antimicrobial activity of these novel ZnO-NPs were considered. MTT assays showed that the inhibitory concentration (IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.