ReviewResearch and reports in tropical medicine2020
Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control.
Review in Research and reports in tropical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- The Prevalence ofArchives of Razi Institute · 2025Pooled it
- Global prevalence of liver disease in human and domestic animals caused by Fasciola: A systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Fasciola spp. in Southeast Asia: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Effects of triclabendazole and its metabolite exposure on the heart-rate-corrected QT intervals: A randomized, placebo- and positive-controlled thorough QT study in healthy individuals.Clinical and translational science · 2023Trial
- Haemocyte-Derived Innate Immune Reactions of the Giant African Snail (Animals : an open access journal from MDPI · 2026Article
- Genotypic evidence of benzimidazole resistance and population structure insights in zoonotic Trichostrongylus colubriformis from Thailand.Parasitology research · 2026Article
- Triclabendazole disrupts mitochondrial electron transportAntimicrobial agents and chemotherapy · 2026Article
- Prevalence and risk factors analysis of fasciolid trematodes with phylogenetic analysis ofHelminthologia · 2026Article
- A practical miracidial motility assay for assessing Fasciola hepatica sensitivity to compounds in vitro.International journal for parasitology. Drugs and drug resistance · 2026Article
- Fasciolosis Reinfection in Japan.Internal medicine (Tokyo, Japan) · 2026Article
- Fraction of sex-inducing substances facilitates growth and body shape change in a Fasciola hepatica/gigantica hybrid: A novel in vitro research platform for studying liver-stage juveniles derived from mice.PLoS neglected tropical diseases · 2026Article
- Development of a qPCR assay for Fasciola spp. identification and a deep amplicon sequencing method for differentiation of fluke species in UK livestock.PLoS neglected tropical diseases · 2026Article
- Article
- Hepatic fascioliasis of emphasizing diagnostic difficulty and the need for high index of suspicion: Four case reports.World journal of clinical cases · 2025Article
- The economic impact of endo- and ectoparasites in dairy cattle.Parasites & vectors · 2025Review
- Comment on "Hepatic Fascioliasis Complicated by Multisite Venous Thromboembolism": Diagnostic Challenges and Clinical Considerations.Clinical case reports · 2025Article
- In vitro co-culture ofVirulence · 2025Article
- Hepatic Fascioliasis Mimicking Hydatid Cyst and Complicated by Portal Vein Thrombosis: A Case Report From Ethiopia.Clinical case reports · 2025Article
- High Efficacy of Triclabendazole/Ivermectin Combination Compared to Triclabendazole Monotherapy for Treating Human Fascioliasis in Upper Egypt: A Prospective Study.Tropical medicine and infectious disease · 2025Article
- Structural Insights and Calcium-Switching Mechanism ofInternational journal of molecular sciences · 2025Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of the reviewThis review aims to critically assess current knowledge about the epidemiology, diagnosis, and management of Fasciola infection in humans. RECENT
findingsFascioliasis is an emerging neglected zoonotic infection affecting the health and wellbeing of human populations. The burden of infection is unclear, and studies have shown the geographic expansion of fascioliasis in human and livestock likely related to climate change. The infection can be asymptomatic or present in acute or chronic forms. Regardless of the presentation, fascioliasis can be associated with long-term complications such as anemia and malnutrition. Early in the infection, antibody testing is the only tool available for diagnosis confirmation. In the chronic forms serology and stool microscopy are helpful. Other tests such as antigen detection and PCR-based methods including isothermal tests have shown promising results. Triclabendazole is the only drug available to treat Fasciola infection. However, reports of resistant infections in livestock and human threaten the clinical care and control of the infection in endemic areas. SUMMARY: Fascioliasis is an emerging infection around the world with an uncertain burden. Lack of standardization of diagnostic testing and treatment alternatives hinder treatment and control of the infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.