Evidence map›Paper›PMID 33273679›Full record

ArticleScientific reports2020

Tellurium doped zinc imidazole framework (Te@ZIF-8) for quantitative determination of hydrogen peroxide from serum of pancreatic cancer patients.

Batool Fatima, Dilshad Hussain, Adeela Saeed, Muhammad Salman Sajid, Saadat Majeed, Rahat Nawaz, Muhammad Naeem Ashiq, Muhammad Najam-Ul-Haq, Rubaida Mehmood

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Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Batool FatimaDepartment of Biochemistry, Bahauddin Zakariya University, Multan, 60800, Pakistan. batoolfatima@bzu.edu.pk.
Dilshad HussainHEJ Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.
Adeela SaeedDepartment of Chemistry, The Women University Multan, Multan, Pakistan.
Muhammad Salman SajidInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Saadat MajeedInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Rahat NawazInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Muhammad Naeem AshiqInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Muhammad Najam-Ul-HaqInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan. najamulhaq@bzu.edu.pk.
Rubaida MehmoodMINAR Cancer Hospital, Pakistan Atomic Energy Commission, Islamabad, Pakistan.
Bahauddin Zakariya University · PKInternational Center for Chemical and Biological Sciences · PKPakistan Atomic Energy Commission · PKThe Women University Multan · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tellurium doped zinc imidazole framework (Te@ZIF-8) is prepared by a two-step hydrothermal strategy for the electrochemical sensing of hydrogen peroxide. Material is characterized by transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). The electrochemical characterization of the MOF modified electrode is done by a three-electrode system. Electrochemical sensing of hydrogen peroxide is made by cyclic voltammetry, amperometry, and impedance measurements. Results demonstrate that Te@ZIF-8 shows a detection limit of 60 µM with linearity up to 0.98855. Material is stable to 1000 cycles with no significant change in electrochemical response. Amperometry depicts the recovery of hydrogen peroxide from human serum up to 101%. Impedance curve reveals the surface of Te@ZIF-8-GCE (glassy carbon electrode) as porous and rough and an interface is developed between analyte ions and the sensing material. Finally, the modified electrode is used for the quantitative determination of hydrogen peroxide from serum samples of pancreatic cancer patients, diagnosed with CA 19-9.

Indexed as

Blood Chemical AnalysisCells, CulturedElectrochemical TechniquesElectrodesHumansHydrogen PeroxideImidazolesLimit of DetectionMetal-Organic FrameworksPancreatic NeoplasmsTelluriumZincHydrogen PeroxideImidazolesMetal-Organic FrameworksTelluriumZinc

Identifiers

PMID33273679
PMCPMC7713350
OpenAlexW3109891811

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.