ArticleScientific reports2020
Education and stroke: evidence from epidemiology and Mendelian randomization study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The burden of psychological distress in stroke survivors: a systematic review and meta-analysis of sociodemographic and behavioral factors.Frontiers in public health · 2026Pooled it
- The Causal Relationship between Angina Pectoris and Gout Based on Two Sample Mendelian Randomization.Pain research & management · 2024Pooled it
- Physical Activity Behavior and Acute Myocardial Infarction, Stroke, and Sepsis Outcomes in Brazil: Insights from Targeted Eigenvector Centrality Networks.International journal of environmental research and public health · 2026Article
- Health-Related Digital Engagement and Incident Stroke Among Older Adults: Prospective Cohort Study.Journal of medical Internet research · 2026Article
- Causal association between rheumatoid arthritis and periodontitis: A Mendelian randomization study.Medicine · 2026Article
- Educational inequalities in stroke knowledge and symptom recognition following a national Danish stroke campaign: a cross-sectional study.BMC public health · 2025Article
- Causal link between type 1 diabetes mellitus and juvenile idiopathic arthritis in Europe.Pediatric research · 2025Article
- Influence of Spiritual Support Program on Quality-of-Life of Stroke Survivors Post Substance Overdose: A Randomized Controlled Trial.Health science reports · 2025Article
- Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers.Stroke · 2025Review
- Mediating factors in the association between educational attainment and stroke: A mendelian randomization study.SSM - population health · 2025Article
- Community resilience and stroke outcomes in older adults: beyond rural-urban classifications.Frontiers in public health · 2025Article
- Risk factors analysis and nomograph model construction of unplanned readmission for ischemic stroke within 31 days in Wenzhou.Frontiers in neurology · 2025Article
- Age at natural menopause and development of chronic diseases in the female population of Kharameh, Iran: A historical cohort study.Health science reports · 2024Article
- No genetic causal association between iron status and pulmonary artery hypertension: Insights from a two-sample Mendelian randomization.Pulmonary circulation · 2024Article
- Time-lagged associations between two adverse childhood experiences and later-life cognitive function through educational attainment and stroke.Journal of the International Neuropsychological Society : JINS · 2024Article
- Social Determinants of Health Framework to Identify and Reduce Barriers to Imaging in Marginalized Communities.Radiology · 2024Review
- The Role of Modifying Risk Factors as Well as Body Mass Index, Waist Circumference and Hip to Waist Ratio as Anthropometric Indicators and Parameters of Obesity in the Occurence of Stroke.Materia socio-medica · 2024Article
- Educational attainment, severity and short-term prognosis of intracerebral haemorrhage.BMJ neurology open · 2024Article
- Prestroke physical activity is associated with admission haematoma volume and the clinical outcome of intracerebral haemorrhage.Stroke and vascular neurology · 2023Article
- Population-based stroke risk profile from a West-African community.eNeurologicalSci · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aim to characterize the association between education and incident stroke (including total stroke, ischemic stroke, and hemorrhagic stroke) and assess whether there is a causal relationship between them. The final sample size was 11,509 in this study from the Atherosclerosis Risk in Communities (ARIC) study. Cox hazard regression models were used to explore the association between education level and incident stroke. Two-sample Mendelian randomization (MR) was used to estimate the causality. During a median follow-up of 25.3 years, 915 cases (8.0%) of stroke occurred. Participants with advanced education level were associated with 25% (HR 0.75; 95% CI 0.62, 0.91) decreased the rate of incident total stroke. Hazard ratio of intermediate and advanced education level for ischemic stroke were 0.82 (0.69, 0.98) and 0.73 (0.60, 0.90) separately. In the MR analysis, we observed evidence that education was likely a negetive causal risk factor for ischemic stroke (OR 0.764, 95% CI 0.585-0.998, P = 0.048). Higher education level was associated with a decreased rate of total stroke and ischemic stroke incident, but not hemorrhagic stroke incident. There might be a protective causal association between education and ischemic stroke (but not total stroke nor hemorrhagic stroke).
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