Evidence map›Paper›PMID 33273563›Full record

ArticleScientific reports2020

Synergistic anti-biofilm effects of Brassicaceae plant extracts in combination with proteinase K against Escherichia coli O157:H7.

Wen Si Hu, Da Min Nam, Joo-Sung Kim, Ok Kyung Koo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. RSC advances · 2026
    Article
  2. Review
  3. Antibacterial and Antibiofilm Activities of Bluestem (International journal of microbiology · 2026
    Article
  4. Review
  5. Inhibitory Effect ofAntibiotics (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Antimicrobial Compounds in Food Packaging.International journal of molecular sciences · 2023
    Review
  9. Antibiofilm Activity and Synergistic Effects of Thymol-Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles with Amikacin against FourThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Synergistic Antibiofilm Efficacy of Thymol and Piperine in Combination with Three Aminoglycoside Antibiotics againstThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wen Si HuDepartment of Food and Nutrition, Gyeongsang National University, Jinju, Republic of Korea.
Da Min NamDepartment of Food and Nutrition, Gyeongsang National University, Jinju, Republic of Korea.
Joo-Sung KimResearch Group of Consumer Safety, Korea Food Research Institute, Wanju-gun, Jeollabuk-do, Republic of Korea.
Ok Kyung KooDepartment of Food and Nutrition, Gyeongsang National University, Jinju, Republic of Korea. okoo@gnu.ac.kr.
Gyeongsang National University · KRKorea Food Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria can form biofilms, complex microbial communities protected from environmental stress, on food contact surfaces. Brassicaceae plant has been shown to contain bioactive compounds with antimicrobial activities. The objective of this study was to evaluate the synergistic effects of Brassicaceae species and proteinase K against E. coli O157:H7 biofilm. We determined the minimum biofilm inhibitory concentration, the fractional inhibitory concentration indexes, and the synergistic inhibitory effect of Raphanus sativus var. longipinnatus, R. sativus, and Brassica oleracea var. acephala extracts with proteinase K on E. coli O157:H7. The biofilm showed a 49% reduction with 2 mg/mL R. sativus. The combination of proteinase K 25 µg/mL significantly increased the effect of 2 mg/mL R. sativus var. longipinnatus and the combined treatment yielded up to 2.68 log reduction on stainless steel coupons. The results showed that the combination of R. sativus var. longipinnatus extract and proteinase K could serve as an anti-biofilm agent with synergistic effects for inhibiting E. coli O157:H7 biofilm on stainless steel surfaces.

Indexed as

Anti-Bacterial AgentsBiofilmsBrassicaceaeDrug SynergismEndopeptidase KEscherichia coliPlant ExtractsStainless SteelAnti-Bacterial AgentsEndopeptidase KPlant ExtractsStainless Steel

Identifiers

PMID33273563
PMCPMC7712827
OpenAlexW3108221114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.