Evidence map›Paper›PMID 33273530›Full record

ArticleScientific reports2020

Tailoring of silica-based nanoporous pod by spermidine multi-activity.

Giulia Della Rosa, Riccardo Di Corato, Sara Carpi, Beatrice Polini, Antonietta Taurino, Lorena Tedeschi, Paola Nieri, Rosaria Rinaldi, Alessandra Aloisi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy.International journal of molecular sciences · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Giulia Della RosaMathematics and Physics "E. De Giorgi" Department, University of Salento, Via Arnesano, 73100, Lecce, Italy.
Riccardo Di CoratoMathematics and Physics "E. De Giorgi" Department, University of Salento, Via Arnesano, 73100, Lecce, Italy.
Sara CarpiDepartment of Pharmacy, University of Pisa, Via Bonanno Pisano, 56126, Pisa, Italy.
Beatrice PoliniDepartment of Pharmacy, University of Pisa, Via Bonanno Pisano, 56126, Pisa, Italy.
Antonietta TaurinoInstitute for Microelectronics and Microsystems (IMM), CNR, Via Monteroni, 73100, Lecce, Italy.
Lorena TedeschiOligonucleotides Laboratory, Institute of Clinical Physiology (IFC), CNR, Via Moruzzi, 56124, Pisa, Italy.
Paola NieriDepartment of Pharmacy, University of Pisa, Via Bonanno Pisano, 56126, Pisa, Italy.
Rosaria RinaldiMathematics and Physics "E. De Giorgi" Department, University of Salento, Via Arnesano, 73100, Lecce, Italy.
Alessandra AloisiInstitute for Microelectronics and Microsystems (IMM), CNR, Via Monteroni, 73100, Lecce, Italy. alessandra.aloisi@cnr.it.
University of Pisa · ITUniversity of Salento · ITInstitute for Microelectronics and Microsystems · ITIstituto di Fisiologia Clinica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquitous in nature, polyamines (PAs) are a class of low-molecular aliphatic amines critically involved in cell growth, survival and differentiation. The polycation behavior is validated as a successful strategy in delivery systems to enhance oligonucleotide loading and cellular uptake. In this study, the chemical features and the functional roles of the PA spermidine are synergistically exploited in the synthesis and bioactive functionalization of SiO

Identifiers

PMID33273530
PMCPMC7712788
OpenAlexW3108568626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.