ArticleScientific reports2020
Blattella germanica displays a large arsenal of antimicrobial peptide genes.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Review
- Review
- Insect immune systems: same same but different but still same.Frontiers in immunology · 2026Review
- Multi-omics of cockroaches infected with Salmonella Typhimurium identifies molecular signatures of vector colonization.BMC genomics · 2025Article
- The gut microbiota confers resistance againstiScience · 2024Article
- Comparative Transcriptomics of Fat Bodies between Symbiotic and Quasi-Aposymbiotic Adult Females ofInternational journal of molecular sciences · 2024Article
- Survival of Salmonella Typhimurium in the hemolymph of the German cockroach vector is limited by both humoral immune factors and hemocytes but not by trehalose metabolism.Journal of medical entomology · 2023Article
- Comparative Efficacy of a Fungal Entomopathogen with a Broad Host Range against Two Human-Associated Pests.Insects · 2022Article
- Identification of the Gene Repertoire of the IMD Pathway and Expression of Antimicrobial Peptide Genes in Several Tissues and Hemolymph of the CockroachInternational journal of molecular sciences · 2022Article
- Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion.Biology open · 2022Article
- Of Cockroaches and Symbionts: Recent Advances in the Characterization of the Relationship betweenLife (Basel, Switzerland) · 2022Review
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Defence systems against microbial pathogens are present in most living beings. The German cockroach Blattella germanica requires these systems to adapt to unhealthy environments with abundance of pathogenic microbes, in addition to potentially control its symbiotic systems. To handle this situation, four antimicrobial gene families (defensins, termicins, drosomycins and attacins) were expanded in its genome. Remarkably, a new gene family (blattellicins) emerged recently after duplication and fast evolution of an attacin gene, which is now encoding larger proteins with the presence of a long stretch of glutamines and glutamic acids. Phylogenetic reconstruction, within Blattellinae, suggests that this duplication took place before the divergence of Blattella and Episymploce genera. The latter harbours a long attacin gene (pre-blattellicin), but the absence of the encoded Glx-region suggests that this element evolved recently in the Blattella lineage. A screening of AMP gene expression in available transcriptomic SR projects of B. germanica showed that, while some AMPs are expressed during almost the whole development, others are restricted to shorter periods. Blattellicins are highly expressed only in adult females. None of the available SR tissue projects could be associated with blattellicins' expression, suggesting that it takes place in other tissues, maybe the gut.
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