Evidence map›Paper›PMID 33273289›Full record

ArticleMedical care2021

Association Between State Policies on Improving Opioid Prescribing in 2 States and Opioid Overdose Rates Among Reproductive-aged Women.

Xu Ji, Sarah C Haight, Jean Y Ko, Shanna Cox, Wanda D Barfield, Kun Zhang, Gery P Guy, Rui Li

Open access · greenAbstract read
In one paragraph

Article in Medical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xu JiDepartment of Pediatrics, Emory University School of Medicine.
Sarah C HaightDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion.
Jean Y KoDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion.
Shanna CoxDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion.
Wanda D BarfieldDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion.
Kun ZhangDivision of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA.
Gery P GuyDivision of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA.
Rui LiDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion.
National Center for Chronic Disease Prevention and Health Promotion · USNational Center for Injury Prevention and Control · USEmory University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundThe opioid overdose epidemic has been declared a public health emergency. Women are more likely than men to be prescribed opioid medications. Some states have adopted policies to improve opioid prescribing, including prescription drug monitoring programs (PDMPs) and pain clinic laws.

objectiveAmong reproductive-aged women, we examined the association of mandatory use laws for PDMPs in Kentucky (concurrent with a pain clinic law) and New York with overdose involving prescription opioids or heroin and opioid use disorder (OUD). STUDY DESIGN, SUBJECTS, AND OUTCOME MEASURES: We conducted interrupted time series analyses estimating outcome changes after policy implementation in Kentucky and New York, compared with geographically close states without these policies (comparison states), using 2010-2014 State Inpatient and State Emergency Department Databases. Outcomes included rates of inpatient discharges and emergency department visits for overdoses involving prescription opioids or heroin and OUD among reproductive-aged women.

resultsRelative to comparison states, following Kentucky's policy change, we found an immediate postpolicy decrease and a decreasing trend in the rate of overdoses involving prescription opioids, an immediate postpolicy increase in the rate of overdoses involving heroin, and a decreasing trend in the OUD rate (P<0.01); New York's policy change was not associated with the assessed outcomes.

conclusionsPDMPs and pain clinic laws, such as those implemented in Kentucky, may be promising strategies to reduce the adverse impacts of high-risk opioid prescribing among reproductive-aged women. As states continue efforts to improve inappropriate opioid prescribing, similar strategies as those adopted in Kentucky merit consideration.

Indexed as

State GovernmentAdultAnalgesics, OpioidDrug PrescriptionsFemaleHealth PolicyHumansInappropriate PrescribingInterrupted Time Series AnalysisKentuckyNew YorkOpiate OverdoseOpioid EpidemicPrescription Drug Monitoring ProgramsAnalgesics, Opioid

Identifiers

PMID33273289
PMCPMC11109529
OpenAlexW3109401667

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.