Evidence map›Paper›PMID 33273139›Full record

ArticleMolecules and cells2020

Long Noncoding RNA Expression Profiling Reveals Upregulation of Uroplakin 1A and Uroplakin 1A Antisense RNA 1 under Hypoxic Conditions in Lung Cancer Cells.

Yuree Byun, Young-Chul Choi, Yongsu Jeong, Jaeseung Yoon, Kwanghee Baek

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuree ByunGraduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0001-9773-1974
Young-Chul ChoiGraduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-1392-0100
Yongsu JeongGraduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-0008-9928
Jaeseung YoonGraduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-6113-5561
Kwanghee BaekGraduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-1364-1355
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia plays important roles in cancer progression by inducing angiogenesis, metastasis, and drug resistance. However, the effects of hypoxia on long noncoding RNA (lncRNA) expression have not been clarified. Herein, we evaluated alterations in lncRNA expression in lung cancer cells under hypoxic conditions using lncRNA microarray analyses. Among 40,173 lncRNAs, 211 and 113 lncRNAs were up- and downregulated, respectively, in both A549 and NCI-H460 cells. Uroplakin 1A (

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticCell HypoxiaCell Line, TumorHumansHypoxia-Inducible Factor 1, alpha SubunitLung NeoplasmsMethylationReproducibility of ResultsRibonucleasesRNA, AntisenseRNA, Long NoncodingRNA, MessengerRNA, Small InterferingRNA StabilityUp-RegulationHypoxia-Inducible Factor 1, alpha SubunitRibonucleasesRNA, AntisenseRNA, Long NoncodingRNA, MessengerRNA, Small InterferingUroplakin IaHypoxiahypoxia-inducible factor 1αmicroarrayuroplakin 1Auroplakin 1A antisense RNA 1

Identifiers

PMID33273139
PMCPMC7772508
OpenAlexW3109557506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.