Evidence map›Paper›PMID 33273114›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Hierarchical routing in carbon metabolism favors iron-scavenging strategy in iron-deficient soil

Caroll M Mendonca, Sho Yoshitake, Hua Wei, Anne Werner, Samantha S Sasnow, Theodore W Thannhauser, Ludmilla Aristilde

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Unique metabolic traits ofJournal of bacteriology · 2026
    Review
  2. Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. DecodingApplied and environmental microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Caroll M MendoncaDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.ORCID 0000-0001-6692-2911
Sho YoshitakeDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.
Hua WeiDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.
Anne WernerDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-2322-6830
Samantha S SasnowDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.
Theodore W ThannhauserRobert W. Holley Center for Agriculture and Health, United States Department of Agriculture, Agricultural Research Service, Cornell University, Ithaca, NY 14853.
Ludmilla AristildeDepartment of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853; ludmilla.aristilde@northwestern.edu.ORCID 0000-0002-8566-1486
Cornell University · USNorthwestern University · USUnited States Department of Agriculture · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-affinity iron (Fe) scavenging compounds, or siderophores, are widely employed by soil bacteria to survive scarcity in bioavailable Fe. Siderophore biosynthesis relies on cellular carbon metabolism, despite reported decrease in both carbon uptake and Fe-containing metabolic proteins in Fe-deficient cells. Given this paradox, the metabolic network required to sustain the Fe-scavenging strategy is poorly understood. Here, through multiple

Indexed as

CarbonCarbon IsotopesCitric Acid CycleEnzymesGluconeogenesisIronMetabolic Networks and PathwaysOligopeptidesPseudomonasSiderophoresSoil MicrobiologySuccinic AcidCarbonCarbon-13Carbon IsotopesEnzymesIronOligopeptidespyoverdinSiderophoresSuccinic Acidbacteriairon limitationmetabolomicsPseudomonas putidasiderophore

Identifiers

PMID33273114
PMCPMC7768705
OpenAlexW3108616886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.