Evidence map›Paper›PMID 33272948›Full record

ArticleAJNR. American journal of neuroradiology2021

Impacts of Glycemic Control on Intracranial Plaque in Patients with Type 2 Diabetes Mellitus: A Vessel Wall MRI Study.

S Jiao, J Huang, Y Chen, Y Song, T Gong, J Lu, T Guo, J Zhang, C Zhang, M Chen

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The Role of Diabetes and SGLT2 Inhibitors in Cerebrovascular Diseases.Current neurology and neuroscience reports · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

S JiaoFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0001-9880-416X
J HuangFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0002-5330-8338
Y ChenNeurology (Y.C., T.Gong).ORCID 0000-0002-3976-8629
Y SongFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0001-5428-1272
T GongNeurology (Y.C., T.Gong).ORCID 0000-0002-9135-8619
J LuNeurosurgery (J.L.), Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, P.R. China, Beijing, China.ORCID 0000-0001-5281-1129
T GuoFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0003-1149-5849
J ZhangFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0002-7990-8913
C ZhangFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0002-1516-3334
M ChenFrom the Departments of Radiology (S.J., J.H., Y.S., T. Guo, J.Z., C.Z., M.C.).ORCID 0000-0001-7777-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe relationship between glycemic control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and glycemic control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND

methodsIn total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and glycemic control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good glycemic control group, and the type 2 diabetes mellitus with poor glycemic control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis.

resultsThe plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor glycemic control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor glycemic control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good glycemic control groups (92.9%, 63.4%, and 72.7%, respectively;

conclusionsPoor glycemic control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.

Indexed as

Glycemic ControlAgedDiabetes Mellitus, Type 2FemaleHumansIntracranial ArteriosclerosisMagnetic Resonance ImagingMaleMiddle AgedPlaque, Atherosclerotic

Identifiers

PMID33272948
PMCPMC7814793

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.