SynthesisJournal of affective disorders2021
Perinatal depressive symptoms and breastfeeding behaviors: A systematic literature review and biosocial research agenda.
Synthesis in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 47 citations in OpenAlex.
- Research and Outcome Priorities for the Canada Prenatal Nutrition Program in Ontario: A Community-Engaged Modified Delphi Study.Maternal & child nutrition · 2026Article
- Desired but Unattained Breastfeeding: A Qualitative Exploration of Maternal Perceptions in a Cultural-Religious Context.Nursing reports (Pavia, Italy) · 2026Article
- Antidepressants and breastfeeding behaviors: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Perinatal depression and breastfeeding: a longitudinal investigation of the bidirectional relationship in Pakistan.Archives of women's mental health · 2026Article
- Physiological Mechanisms in Pregnancy and Their Relevance to the Clinical Management of Perinatal Mental Illness.Journal of clinical medicine · 2026Review
- Article
- Mid-Pregnancy Maternal Anxiety Mediates the Association Between Maternal Chronotype and Breastfeeding Duration.Nutrients · 2026Article
- A Population-Based Cohort Study of Early Infant Feeding Initiation in Maternal Bipolar Disorder.Bipolar disorders · 2025Article
- Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-Term Infants Born Via Cesarean Section: Protocol for a Pilot Randomized Controlled Trial.Journal of human lactation : official journal of International Lactation Consultant Association · 2025Article
- Differences in infant feeding methods at one month postpartum among women with psychiatric disorders and factors influencing exclusive breastfeeding.Child and adolescent psychiatry and mental health · 2025Article
- An overview of reviews of breastfeeding barriers and facilitators: Analyzing global research trends and hotspots.Global epidemiology · 2025Review
- Repetitive Negative Thinking is Associated With Depression and Feeding Status at 3 and 6 Months Postpartum: Retrospective Study.Alpha psychiatry · 2025Article
- Association of Perinatal Depressive Symptoms with Breastfeeding.Alpha psychiatry · 2024Article
- Breast milk oxytocin and s-IgA modulate infant biomarkers and social engagement; The role of maternal anxiety.Comprehensive psychoneuroendocrinology · 2024Article
- Associations between food insecurity and child and parental physical, nutritional, psychosocial and economic well-being globally during the first 1000 days: A scoping review.Maternal & child nutrition · 2024Article
- Breastfeeding and Postpartum Depression: A Review of Relationships and Potential Mechanisms.Current psychiatry reports · 2023Review
- A Probiotic Intervention With Bifidobacterium longum NCC3001 on Perinatal Mood Outcomes (PROMOTE Study): Protocol for a Decentralized Randomized Controlled Trial.JMIR research protocols · 2023Article
- The trajectories of physical growth in 4 months postnatal corrected age among preterm infants discharged from neonatal intensive care units and associated factors: A prospective study.International journal of nursing sciences · 2023Article
- Trajectory of Perinatal Depressive Symptoms from the Second Trimester to Three Months Postpartum and Its Association with Sleep Quality.International journal of women's health · 2023Article
- Associations between breastfeeding intention, breastfeeding practices and post-natal depression during the COVID-19 pandemic: A multi-country cross-sectional study.Maternal & child nutrition · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundBreastfeeding is recommended to improve maternal and infant health globally. Depression has been posited to negatively impact breastfeeding, although potential causal and bidirectional pathways between these two phenomena have not been sufficiently characterized. We therefore conducted a systematic review to critically evaluate available evidence on the relationship between perinatal depressive symptoms and breastfeeding behaviors; to identify knowledge gaps and propose a biosocial research agenda to advance our understanding of this topic.
methodsA systematic search strategy was applied across seven databases. Data were extracted and aggregated using the matrix method to provide a narrative synthesis of findings.
resultsThirty-eight studies from 20 countries spanning 1988 through 2018 fit the inclusion criteria. In general, methods across studies were heterogeneous. Fourteen different tools were used to measure perinatal depressive symptoms. Nearly half the studies did not provide breastfeeding definitions. No studies from low-income countries met inclusion criteria. More than half (63%) of studies demonstrated a negative association between depressive symptoms across the perinatal period and less exclusive breastfeeding and/or shorter breastfeeding durations. LIMITATIONS: Heterogeneity in study design, definitions, assessment tools, and measurement time points limited the comparability of study findings. Causality cannot be assessed.
conclusionsAvailable evidence suggests perinatal depressive symptoms negatively associated with breastfeeding exclusivity and duration, which can lead to suboptimal infant nutrition and detrimental impacts on maternal mental and physical health. To better understand this relationship, we propose including consistent operationalization and assessment of depression and breastfeeding globally and concurrent repeated measures of key biological and social factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.