Evidence map›Paper›PMID 33272312›Full record

ArticleClinical epigenetics2020

DNA methylation patterns of β-globin cluster in β-thalassemia patients.

Xiuqin Bao, Yangjin Zuo, Diyu Chen, Cunyou Zhao

Open access · goldAbstract read
In one paragraph

Article in Clinical epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Xiuqin BaoDepartment of Medical Genetics, School of Basic Medical Sciences, Guangdong Technology and Engineering Research Center for Molecular Diagnostics of Human Genetic Diseases, and Guangdong Engineering and Technology Research Center for Genetic Testing, Southern Medical University, Guangzhou, 510515, China.
Yangjin ZuoDepartment of Medical Genetics, School of Basic Medical Sciences, Guangdong Technology and Engineering Research Center for Molecular Diagnostics of Human Genetic Diseases, and Guangdong Engineering and Technology Research Center for Genetic Testing, Southern Medical University, Guangzhou, 510515, China.
Diyu ChenDepartment of Medical Genetics, School of Basic Medical Sciences, Guangdong Technology and Engineering Research Center for Molecular Diagnostics of Human Genetic Diseases, and Guangdong Engineering and Technology Research Center for Genetic Testing, Southern Medical University, Guangzhou, 510515, China.
Cunyou ZhaoDepartment of Medical Genetics, School of Basic Medical Sciences, Guangdong Technology and Engineering Research Center for Molecular Diagnostics of Human Genetic Diseases, and Guangdong Engineering and Technology Research Center for Genetic Testing, Southern Medical University, Guangzhou, 510515, China. cyzhao@smu.edu.cn.ORCID 0000-0001-6116-4584
Southern Medical University · CNGuangxi Maternal and Child Health Hospital · CNMinistry of Education · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReactivation of fetal hemoglobin (HbF, α

resultsHere, we evaluated DNA methylation patterns of the β-globin cluster from peripheral bloods of 105 β

conclusionsOur findings revealed methylation patterns in β-globin cluster associated with β

Indexed as

AdolescentAdultbeta-Globinsbeta-ThalassemiaBone MarrowCase-Control StudiesChildChild, PreschoolCpG IslandsDNA MethylationEpigenesis, GeneticFetal BloodFetal Hemoglobingamma-GlobinsHumansPromoter Regions, Geneticbeta-GlobinsFetal Hemoglobingamma-GlobinsBone marrowCord bloodDevelopmental stageFetal hemoglobinMethylation patternsβ0 thalassemia patientsβ-globin cluster

Identifiers

PMID33272312
PMCPMC7712619
OpenAlexW3106810446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.