SynthesisJournal of orthopaedic surgery and research2020
Risk factors for adjacent segment degeneration after posterior lumbar fusion surgery in treatment for degenerative lumbar disorders: a meta-analysis.
Synthesis in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06029764 (Extended One-level Interbody Fusion for Adjacent Vacuum Phenomenon in Lumbar Degenerative Disc Disease), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Extended One-level Interbody Fusion for Adjacent Vacuum Phenomenon in Lumbar Degenerative Disc Disease
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Thirty-day unplanned readmission rates and risk factors in spine surgery: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Incidence and risk factors of distal adjacent disc degeneration in adolescent idiopathic scoliosis patients undergoing fusion surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Development and validation of explainable machine learning models to predict the risk of adjacent segment disease after lumbar fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Dynamic versus rigid lumbar fixation: A multimodal comparison of paraspinal muscle morphology, electromyography, and functional outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Low-Profile Posterior Lumbar Fusion Combined With Proximal Interlaminar Coflex Dynamic Fixation for Lumbar Degenerative Diseases: A Comparative Study.Orthopaedic surgery · 2026Article
- Sarcopenia, paraspinal muscle degeneration, and bone quality as prognostic factors for adjacent segment degeneration or disease after lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Upright MRI Follow-Up for Decompression and Interlaminar Stabilization in Low-Grade L4/L5 Spondylolisthesis Suggests Reduced Reoperation Rates Compared With Fusion or Decompression Alone.International journal of spine surgery · 2026Article
- Risk Factors for Postoperative Complications in Different Fusion Surgical Approaches for Lumbar Degenerative Diseases.Journal of clinical medicine · 2026Article
- Comparable Fusion Response, but Increased Inflammatory Response, withJournal of clinical medicine · 2026Article
- Risk Factors and Clinical Significance for Retrolisthesis of Adjacent Segment After Transforaminal Lumbar Interbody Fusion.Orthopaedic surgery · 2026Article
- Association of operative-level segmental lordosis correction with reciprocal changes in sagittal and spinopelvic parameters after single-level lateral lumbar interbody fusion at L4-5.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Analysis of Risk Factors for Adjacent Segment Disease After Lumbar Facet Joint Fusion.Orthopaedic surgery · 2026Article
- Advancing Scoliosis Treatment with Patient-Specific Functionally Graded NiTi-SMA Rods: Key Considerations and Development Objectives.Bioengineering (Basel, Switzerland) · 2026Review
- Interspinous process fixation versus posterior lumbar interbody fusion following decompression for single-level grade I degenerative spondylolisthesis: a retrospective propensity score-matched study.Journal of orthopaedic surgery and research · 2026Article
- Clinical efficacy of 3D-printed guide plates in single-level lumbar degenerative disease: a retrospective comparative study.BMC surgery · 2026Article
- The Efficacy of Prone Single-Position Lateral Lumbar Interbody Fusion for Symptomatic Cranial Adjacent Segment Degeneration.Journal of clinical medicine · 2026Article
- Preventing adjacent segment disease after lumbar fusion: a new perspective emphasizing individualized factors.Quantitative imaging in medicine and surgery · 2026Article
- Oblique lateral interbody fusion versus transforaminal lumbar interbody fusion for single-level lumbar adjacent segment disease: a retrospective comparative study of clinical and radiographic outcomes.Frontiers in surgery · 2026Article
- Indications of Clinical Application of L5 Laminar Hook for the Surgical Correction of Degenerative Sagittal Imbalance.Medicina (Kaunas, Lithuania) · 2025Article
- Endoscopic spinal surgery in adjacent segment disease-a viable alternative to transforaminal lumbar interbody fusion: a case report.Journal of spine surgery (Hong Kong) · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designA meta-analysis.
objectiveWe performed a meta-analysis to explore the incidence and risk factors of adjacent segment degeneration (ASD) after posterior lumbar fusion surgery.
methodsAn extensive search of the literature was performed in English database of PubMed, Embase, and Cochrane Library, and Chinese database of CNKI and WANFANG (up to May 2020). We collected factors including demographic data, surgical factor, and sagittal parameters. Data analysis was conducted with RevMan 5.3 and STATA 12.0.
resultsFinally, 19 studies were included in the final analysis. In our study, the rate of ASD after posterior lumbar fusion surgery was 18.6% (540 of 2896). Our data also showed that mean age, body mass index (BMI), the history of smoking and hypertension, preoperative adjacent disc degeneration, long-segment fusion, preoperative superior facet violation, high lumbosacral joint angle, pre- and post-operative L1-S1 sagittal vertical axis (SVA), post-operative lumbar lordosis (LL), and preoperative pelvic incidence (PI) were associated with the development of ASD. However, gender, history of diabetes, bone mineral density (BMD), preoperative Oswestry Disability Index (ODI) and Japanese Orthopedic Association (JOA), the type of fusion (PLIF vs TLIF), type of bone graft (auto- vs allograft), fusion to S1(vs non-fusion to S1), diagnose (lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis), preoperative pelvic tilt (PT), LL and sacral slope (SS), post-operative SS, PT and PI were not associated with the development of ASD.
conclusionsIn our study, many factors were correlated with the risk of ASD after posterior lumbar fusion surgery. We hope this article can provide a reference for spinal surgeons in treatment for lumbar degenerative diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.