Evidence map›Paper›PMID 33272208›Full record

SynthesisBMC geriatrics2020

The impact of interventions on management of frailty in hospitalized frail older adults: a systematic review and meta-analysis.

Zahra Rezaei-Shahsavarloo, Foroozan Atashzadeh-Shoorideh, Robbert J J Gobbens, Abbas Ebadi, Gholamreza Ghaedamini Harouni

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06469723 (Protocol for Inpatient Nursing Frailty Assessment), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 4 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06469723 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Protocol for Inpatient Nursing Frailty Assessment (INFA): Comprehensive Geriatric Assessment and Multidisciplinary Intervention for Frail Hospitalised Older Adults

TypeinterventionalSponsorTan Tock Seng HospitalRan2024 to 2026Enrolled300ConditionsFunctional Status, FrailtyArmsINFA Program
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 126 citations in OpenAlex.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Zahra Rezaei-ShahsavarlooStudent Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Foroozan Atashzadeh-ShooridehDepartment of Psychiatric Nursing and Management, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. f_atashzadeh@sbmu.ac.ir.ORCID 0000-0002-6144-6001
Robbert J J GobbensFaculty of Health, Sports and Social Work, Inholland University of Applied Sciences, Amsterdam, The Netherlands.
Abbas EbadiBehavioral Sciences Research Center, Life style institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Gholamreza Ghaedamini HarouniSocial Welfare Management Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Baqiyatallah University of Medical Sciences · IRIranshahr University · IRShahid Beheshti University of Medical Sciences · IRUniversity of Antwerp · BEUniversity of Social Welfare and Rehabilitation Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the most challenging issues for the elderly population is the clinical state of frailty. Frailty is defined as a cumulative decline across psychological, physical, and social functioning. Hospitalization is one of the most stressful events for older people who are becoming frail. The aim of the present study was to determine the effectiveness of interventions focused on management of frailty in hospitalized frail older adults.

methodsA systematic review and meta-analysis of research was conducted using the Medline, Embase, Cochrane, ProQuest, CINAHL, SCOPUS and Web of Science electronic databases for papers published between 2000 and 2019. Randomized controlled studies were included that were aimed at the management of frailty in hospitalized older adults. The outcomes which were examined included frailty; physical, psychological, and social domains; length of stay in hospital; re-hospitalization; mortality; patient satisfaction; and the need for post discharge placement.

resultsAfter screening 7976 records and 243 full-text articles, seven studies (3 interventions) were included, involving 1009 hospitalized older patients. The quality of these studies was fair to poor and the risk of publication bias in the studies was low. Meta-analysis of the studies showed statistically significant differences between the intervention and control groups for the management of frailty in hospitalized older adults (ES = 0.35; 95% CI: 0. 067-0.632; z = 2.43; P < 0.015). However, none of the included studies evaluated social status, only a few of the studies evaluated other secondary outcomes. The analysis also showed that a Comprehensive Geriatric Assessment unit intervention was effective in addressing physical and psychological frailty, re-hospitalization, mortality, and patient satisfaction.

conclusionsInterventions for hospitalized frail older adults are effective in management of frailty. Multidimensional interventions conducted by a multidisciplinary specialist team in geriatric settings are likely to be effective in the care of hospitalized frail elderly. Due to the low number of RCTs carried out in a hospital setting and the low quality of existing studies, there is a need for new RCTs to be carried out to generate a protocol appropriate for frail older people.

Indexed as

Frail ElderlyFrailtyAftercareAgedAged, 80 and overGeriatric AssessmentHumansPatient DischargeFrail elderlyFrailtyHospitalizationInterventionSystematic review; meta-analysis

Identifiers

PMID33272208
PMCPMC7712609
OpenAlexW3110250299

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.